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Leukocyte cell-derived chemotaxin-2
go.drugbank.com/bio_entities/BE0011408TargetHumansHas a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation (PubMed:9524238). Does not show metalloendopeptidase activity (PubMed:27334921)
Polypeptides: Leukocyte cell-derived chemotaxin-2Synonyms: LECT-2Cytochrome c oxidase subunit 2
go.drugbank.com/bio_entities/BE0003385TargetHumansThe BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix … Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit
Polypeptides: Cytochrome c oxidase subunit 2NADH-ubiquinone oxidoreductase chain 2
go.drugbank.com/bio_entities/BE0000655TargetHumansCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:16996290). Essential ...
Polypeptides: NADH-ubiquinone oxidoreductase chain 2Synonyms: NADH dehydrogenase subunit 2Alpha-1-acid glycoprotein 2
go.drugbank.com/bio_entities/BE0003663TargetHumansFunctions as a transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modu...
Polypeptides: Alpha-1-acid glycoprotein 2Synonyms: AGP 2, OMD 2Immunoglobulin heavy variable 1-2
go.drugbank.com/bio_entities/BE0004264TargetHumansV region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Polypeptides: Immunoglobulin heavy variable 1-2Protein-glutamine gamma-glutamyltransferase 2
go.drugbank.com/bio_entities/BE0001035TargetEnzymeHumansCatalyzes serotonylation of 'Gln-5' of histone H3 (H3Q5ser) during serotonergic neuron differentiation, thereby facilitating transcription (PubMed:30867594). … Under physiological conditions, the protein cross-linking activity is inhibited by GTP; inhibition is relieved by Ca(2+) in response to various stresses (PubMed:18092889, PubMed:7592956, PubMed:7649299
Polypeptides: Protein-glutamine gamma-glutamyltransferase 2Synonyms: TGase-2, Transglutaminase-2Atrial natriuretic peptide receptor 2
go.drugbank.com/bio_entities/BE0000997TargetHumansReceptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth
Polypeptides: Atrial natriuretic peptide receptor 2Proteasome subunit alpha type-2
go.drugbank.com/bio_entities/BE0003911TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...
Polypeptides: Proteasome subunit alpha type-2Synonyms: alpha-2, Proteasome subunit alpha-2M-phase inducer phosphatase 2
go.drugbank.com/bio_entities/BE0001705TargetHumansTyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression (PubMed:1836978, PubMed:20360007). Directly dephosphorylates CDK1 and stimulates its kinase activity (PubMed:20360007). Required for G2/M p...
Polypeptides: M-phase inducer phosphatase 2Inward rectifier potassium channel 2
go.drugbank.com/bio_entities/BE0027705TargetRatInward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as externa...
Polypeptides: Inward rectifier potassium channel 2Synonyms: Potassium channel, inwardly rectifying subfamily J member 2