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Displaying results 61 - 70 of 470 in total
  1. Target

    Testicular acid phosphatase

    go.drugbank.com/bio_entities/BE0019349
    TargetHumans

    Regulates odontoblast cell fate via its extracellular catalytic domain by inhibiting proliferation and promoting differentiation (By similarity)

    Polypeptides: Testicular acid phosphataseSynonyms: Acid phosphatase 4
  2. Target

    Probable fatty acid synthase Fas (Fatty acid synthetase)

    go.drugbank.com/bio_entities/BE0009744
    TargetMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

    Polypeptides: Probable fatty acid synthase Fas (Fatty acid synthetase)
  3. Target

    Prostatic acid phosphatase

    go.drugbank.com/bio_entities/BE0001102
    TargetHumans

    Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (PubMed:10506173, PubMed:15280042) … A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins

    Polypeptides: Prostatic acid phosphataseSynonyms: Acid phosphatase 3
  4. Target

    Bile acid receptor

    go.drugbank.com/bio_entities/BE0001777
    TargetHumans

    Receptor for bile acids (BAs) such as chenodeoxycholic acid (CDCA), lithocholic acid, deoxycholic acid (DCA) and allocholic acid (ACA). … ), VLDLR and SDC1 (involved in the hepatic uptake of LDL and IDL remnants), and inhibiting expression of MTTP (involved in VLDL assembly (PubMed:12554753, PubMed:12660231, PubMed:15337761).

    Polypeptides: Bile acid receptorFunction: bile acid binding
  5. Target

    alpha1-acid glycoprotein

    go.drugbank.com/bio_entities/BE0004879
    TargetCarrierHumans

    Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction … Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction

    Polypeptides: Alpha-1-acid glycoprotein 1, Alpha-1-acid glycoprotein 2
  6. Target

    Retinoic acid receptor beta

    go.drugbank.com/bio_entities/BE0000206
    TargetHumans

    Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes … Receptor for retinoic acid.

    Polypeptides: Retinoic acid receptor beta
  7. Target

    Hydroxycarboxylic acid receptor 3

    go.drugbank.com/bio_entities/BE0000836
    TargetHumans

    Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet (PubMed:12522134) … G protein-coupled receptor for 3-hydroxyoctanoate, a fatty acid beta-oxidation intermediate.

    Polypeptides: Hydroxycarboxylic acid receptor 3Synonyms: Nicotinic acid receptor 2
  8. Target

    Delta-aminolevulinic acid dehydratase

    go.drugbank.com/bio_entities/BE0001285
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). … Catalyzes an early step in the biosynthesis of tetrapyrroles.

    Polypeptides: Delta-aminolevulinic acid dehydratase
  9. Target

    Delta-aminolevulinic acid dehydratase

    go.drugbank.com/bio_entities/BE0002002
    TargetEscherichia coli (strain K12)

    Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.

    Polypeptides: Delta-aminolevulinic acid dehydratase
  10. Target

    N-succinylamino acid racemase

    go.drugbank.com/bio_entities/BE0003211
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Catalyzes both N-succinylamino acid racemization and OSB synthesis at equivalent rates (PubMed:24872444). … Acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of N-succinyl-L-phenylglycine and N-succinyl-D/L-phenylalanine (PubMed:24872444, PubMed:25875730).

    Polypeptides: N-succinylamino acid racemaseSynonyms: N-acylamino acid racemase, o-succinylbenzoic acid synthase