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Chlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalChlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventi...
Categories: Sodium Chloride Symporter Inhibitors, chlortalidone and potassiumGlyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigational[L8123] Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and calcium ion concentrations.
Electrolyte imbalance
go.drugbank.com/conditions/DBCOND0015850Synonyms: Fluid/electrolyte/acid-base or electrolyte disorders (& [potassium] or [sodium])Rabeprazole Action Pathway
smpdb.ca/view/SMP0000229Drug actionA chloride ion is transported into the gastric endothelial cell through a chloride anion exchanger and is transported out of the cell through a chloride intracellular channel protein 2, back into the gastric … The potassium transporting ATPase also converts water and ATP to a phosphate molecule and ADP. Alongside the transporters, potassium is brought into the cell.
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1Roxatidine Acetate Action Pathway
smpdb.ca/view/SMP0000734Drug actionA chloride ion is transported into the gastric endothelial cell through a chloride anion exchanger and is transported out of the cell through a chloride intracellular channel protein 2, back into the gastric … The potassium transporting ATPase also converts water and ATP to a phosphate molecule and ADP. Alongside the transporters, potassium is brought into the cell.
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1Ranitidine Action Pathway
smpdb.ca/view/SMP0000230Drug actionA chloride ion is transported into the gastric endothelial cell through a chloride anion exchanger and is transported out of the cell through a chloride intracellular channel protein 2, back into the gastric … The potassium transporting ATPase also converts water and ATP to a phosphate molecule and ADP. Alongside the transporters, potassium is brought into the cell.
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1Gastric Acid Production
smpdb.ca/view/SMP0000589PhysiologicalHowever, it is also constituted of potassium chloride (KCl) and sodium chloride (NaCl). … Moreover, the chloride and potassium ions are transported into the stomach lumen through their own channels so that hydrogen ions and/or potassium ions can form an ionic bond with chloride ions to form
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1Omeprazole Action Pathway (old)
smpdb.ca/view/SMP0000226Drug actionThis active metabolite then binds covalently to the potassium-transporting ATPase protein subunits, found at the secretory surface of the gastric parietal cell, preventing any stimulus.
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1Lansoprazole Action Pathway (old)
smpdb.ca/view/SMP0000227Drug actionThis active metabolite then binds covalently to the potassium-transporting ATPase protein subunits, found at the secretory surface of the gastric parietal cell, preventing any stimulus.
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1