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5-hydroxytryptamine receptor 3A
go.drugbank.com/bio_entities/BE0000311TargetHumansForms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons
Polypeptides: 5-hydroxytryptamine receptor 3ASynonyms: Serotonin receptor 3A, 5-hydroxytryptamine receptor 3Thyroid hormone receptor beta
go.drugbank.com/bio_entities/BE0000315TargetHumansNuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine
Polypeptides: Thyroid hormone receptor betaSynonyms: Nuclear receptor subfamily 1 group A member 2Follicle-stimulating hormone receptor
go.drugbank.com/bio_entities/BE0000387TargetHumansG protein-coupled receptor for follitropin, the follicle-stimulating hormone (PubMed:11847099, PubMed:24058690, PubMed:24692546). … Has diverse extragonadal functions: signals via a GNAI2-coupled FSHR on osteoclasts and their precursors, resulting in activation of MEK/ERK, NF-kappa-B, and AKT pathways and thus increases osteoclastogenesis
Polypeptides: Follicle-stimulating hormone receptorSynonyms: Follitropin receptorMuscarinic acetylcholine receptor M4
go.drugbank.com/bio_entities/BE0000405TargetHumansThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action
Polypeptides: Muscarinic acetylcholine receptor M4Function: G protein-coupled acetylcholine receptor activityDelta-type opioid receptor
go.drugbank.com/bio_entities/BE0000420TargetHumansG protein-coupled receptor that functions as a receptor for endogenous enkephalins and for a subset of other opioids.
Polypeptides: Delta-type opioid receptorFunction: G protein-coupled enkephalin receptor activity5-hydroxytryptamine receptor 2A
go.drugbank.com/bio_entities/BE0000451TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895, PubMed:21645528, PubMed:22300836, PubMed:35084960, PubMed:38552625). … Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed
Polypeptides: 5-hydroxytryptamine receptor 2ASynonyms: Serotonin receptor 2ANeurotensin receptor type 2
go.drugbank.com/bio_entities/BE0000464TargetHumansReceptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Neurotensin receptor type 2Synonyms: Levocabastine-sensitive neurotensin receptorMelatonin receptor type 1A
go.drugbank.com/bio_entities/BE0000515TargetHumansHigh affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. … The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Polypeptides: Melatonin receptor type 1ASynonyms: Mel-1A-R, Mel1a receptorMuscarinic acetylcholine receptor M2
go.drugbank.com/bio_entities/BE0000560TargetHumansMuscarinic receptor for acetylcholine, a neurotransmitter found in the brain, neuromuscular junctions and the autonomic ganglia (PubMed:24256733, PubMed:3443095, PubMed:36690613).
Polypeptides: Muscarinic acetylcholine receptor M2Alpha-2B adrenergic receptor
go.drugbank.com/bio_entities/BE0000572TargetHumansAlpha-2 adrenergic receptors are G protein-coupled receptors for catecholamines that activate G(i/o) protein pathway, thereby promoting adenylyl cyclase inhibition, ERK1/2 stimulation, and voltage-gated calcium channels suppression (PubM...
Polypeptides: Alpha-2B adrenergic receptorSynonyms: Alpha-2 adrenergic receptor subtype C2