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Spike glycoprotein
go.drugbank.com/bio_entities/BE0010022TargetSARS-CoV-2The stalk domain of S contains three hinges, giving the head unexpected orientational freedom (PubMed:32817270).
Synonyms: S glycoproteinOlanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigational[A176996] Its chemical structure contains a thieno[2,3-b][1,5]benzodiazepine core, and has a methyl group attached to the piperazine ring. … Olanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent.
Mixtures: TARGET 3 MG /25 MG KAPSUL, 90 ADET, TARGET 6 MG /25 MG KAPSUL, 90 ADETCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesAdrenal Cushing Syndrome
go.drugbank.com/conditions/DBCOND0148294Drugs: MitotaneSynonyms: Cushing s SyndromeAdult Onset Still's Disease
go.drugbank.com/conditions/DBCOND0136303Drugs: CanakinumabSynonyms: Adult-Onset Still´s DiseaseTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalTranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. … It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent.
Synonyms: trans-4-aminomethylcyclohexane-1-carboxylic acid, trans-4-(Aminomethyl)cyclohexanecarboxylic acidInternational brands: Cyclo-FProtein S100-B
go.drugbank.com/bio_entities/BE0001177TargetHumansSmall zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain (PubMed:20950652, PubMed:6487634). Weakly binds calcium but binds zinc very tightly-di...
Synonyms: S-100 protein beta chain, S-100 protein subunit betaBortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigationalBortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. … [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid, N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamideProtein S100-A1
go.drugbank.com/bio_entities/BE0001090TargetHumansSmall calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation (PubMed:12804600). In response to an increase in intracellular Ca(2+) l...
Synonyms: S-100 protein alpha chain, S-100 protein subunit alpha