Search

Displaying results 711 - 720 of 3729 in total
  1. Target

    Muscarinic acetylcholine receptor M3

    go.drugbank.com/bio_entities/BE0000045
    TargetHumans

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M3
  2. Target

    Muscarinic acetylcholine receptor M1

    go.drugbank.com/bio_entities/BE0000092
    TargetHumans

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M1Function: G protein-coupled acetylcholine receptor activity
  3. Target

    Cysteinyl leukotriene receptor 2

    go.drugbank.com/bio_entities/BE0000099
    TargetHumans

    Receptor for cysteinyl leukotrienes. The response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system.

    Polypeptides: Cysteinyl leukotriene receptor 2Synonyms: G protein-coupled receptor HG57, G protein-coupled receptor GPCR21
  4. Target

    Lutropin-choriogonadotropic hormone receptor

    go.drugbank.com/bio_entities/BE0000134
    TargetHumans

    Receptor for lutropin-choriogonadotropic hormone (PubMed:11847099). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099)

    Polypeptides: Lutropin-choriogonadotropic hormone receptorSynonyms: Luteinizing hormone receptor
  5. Target

    Retinoic acid receptor gamma

    go.drugbank.com/bio_entities/BE0000144
    TargetHumans

    Receptor for retinoic acid.

    Polypeptides: Retinoic acid receptor gammaSynonyms: Nuclear receptor subfamily 1 group B member 3
  6. Target

    Toll-like receptor 7

    go.drugbank.com/bio_entities/BE0000155
    TargetHumans

    Endosomal receptor that plays a key role in innate and adaptive immunity (PubMed:14976261, PubMed:32433612).

    Polypeptides: Toll-like receptor 7
  7. Target

    Gonadotropin-releasing hormone receptor

    go.drugbank.com/bio_entities/BE0000203
    TargetHumans

    This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling … Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH

    Polypeptides: Gonadotropin-releasing hormone receptorSynonyms: GnRH receptor
  8. Target

    Activin receptor type-1

    go.drugbank.com/bio_entities/BE0000264
    TargetHumans

    May promote the expression of HAMP, potentially via its interaction with BMP6 (By similarity) … As a type I receptor, forms heterotetrameric receptor complexes with the type II receptors AMHR2, ACVR2A or ACVR2B (PubMed:17911401).

    Polypeptides: Activin receptor type-1Synonyms: Activin receptor type I, Activin receptor-like kinase 2
  9. Target

    Alpha-2A adrenergic receptor

    go.drugbank.com/bio_entities/BE0000289
    TargetHumans

    Alpha-2 adrenergic receptors are G protein-coupled receptors for catecholamines that activate the G(i/o) protein pathway, thereby promoting adenylyl cyclase inhibition, ERK1/2 stimulation, and voltage-gated calcium channels suppression (...

    Polypeptides: Alpha-2A adrenergic receptorSynonyms: Alpha-2 adrenergic receptor subtype C10
  10. Target

    Melatonin receptor type 1B

    go.drugbank.com/bio_entities/BE0000327
    TargetHumans

    High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. … The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity

    Polypeptides: Melatonin receptor type 1BSynonyms: Mel1b receptor