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Displaying results 7191 - 7200 of 10000 in total
  1. Pathway

    Cardiolipin Biosynthesis CL(20:3(11Z,14Z,17Z)/20:4(5Z,8Z,11Z,14Z)/18:4(6Z,9Z,12Z,15Z)/20:2(11Z,14Z))

    smpdb.ca/view/SMP0250385
    Metabolic

    Third, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
  2. Pathway

    Cardiolipin Biosynthesis CL(20:3(11Z,14Z,17Z)/20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/18:2(9Z,12Z))

    smpdb.ca/view/SMP0250425
    Metabolic

    Third, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
  3. Pathway

    Cardiolipin Biosynthesis CL(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/20:3(11Z,14Z,17Z)/20:2(11Z,14Z))

    smpdb.ca/view/SMP0250616
    Metabolic

    Third, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
  4. Pathway

    Cardiolipin Biosynthesis CL(18:4(6Z,9Z,12Z,15Z)/20:2(11Z,14Z)/20:3(11Z,14Z,17Z)/18:4(6Z,9Z,12Z,15Z))

    smpdb.ca/view/SMP0495505
    Metabolic

    Third, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
  5. Target

    Trypsin-3

    go.drugbank.com/bio_entities/BE0001583
    TargetHumans

    Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors

    Polypeptides: Trypsin-3Synonyms: Serine protease 3, Serine protease 4
  6. Target

    Calpain-3

    go.drugbank.com/bio_entities/BE0003470
    TargetHumans

    Calcium-regulated non-lysosomal thiol-protease. Proteolytically cleaves CTBP1 at 'His-409'. Mediates, with UTP25, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329)

    Polypeptides: Calpain-3Synonyms: CANP 3, Calcium-activated neutral proteinase 3
  7. Target

    Aquaporin-3

    go.drugbank.com/bio_entities/BE0009664
    TargetTransporterHumans

    Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed:12239222, PubMed:30420639). Could also b...

    Polypeptides: Aquaporin-3Synonyms: AQP-3, Aquaglyceroporin-3
  8. Target

    Glypican-3

    go.drugbank.com/bio_entities/BE0010527
    TargetHumans

    Cell surface proteoglycan (PubMed:14610063). Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins (By simil...

    Polypeptides: Glypican-3Synonyms: GTR2-2
  9. Target

    Caspase-3

    go.drugbank.com/bio_entities/BE0010922
    TargetRat

    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis, it proteolytically cleaves poly(ADP-ribose) polymerase PARP1 at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regul...

    Polypeptides: Caspase-3Synonyms: CASP-3
  10. Pathway

    Acylcarnitine 2-Hydroxyundec-3-enoylcarnitine

    smpdb.ca/view/SMP0123957
    Metabolic

    2-Hydroxyundec-3-enoylcarnitine is an acylcarnitine. … Once in the matrix, 2-hydroxyundec-3-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form 2-hydroxyundec-3-enoyl-CoA

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial