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Displaying results 7231 - 7240 of 10000 in total
  1. Target

    Caspase-3

    go.drugbank.com/bio_entities/BE0010922
    TargetRat

    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis, it proteolytically cleaves poly(ADP-ribose) polymerase PARP1 at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regul...

    Polypeptides: Caspase-3Synonyms: CASP-3
  2. Pathway

    Acylcarnitine 2-Hydroxyundec-3-enoylcarnitine

    smpdb.ca/view/SMP0123957
    Metabolic

    2-Hydroxyundec-3-enoylcarnitine is an acylcarnitine. … Once in the matrix, 2-hydroxyundec-3-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form 2-hydroxyundec-3-enoyl-CoA

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  3. Indication

    Invasive Infection caused by Streptococcus pneumoniae serotype 4

    go.drugbank.com/conditions/DBCOND0093593
    Drugs: Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
    Synonyms: Invasive Infection caused by Streptococcus pneumoniae serotype 4
  4. Drug

    Cholestyramine

    go.drugbank.com/drugs/DB01432
    ApprovedInvestigational

    Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins.

    Categories: Compounds used in a research, industrial, or household settingProducts: COLESTIRAMINA 4 G., COLESTIRAMINA 4 G POLVO
  5. Drug

    Zinc oxide

    go.drugbank.com/drugs/DB09321
    ApprovedInvestigational

    Zinc oxide is an inorganic compound used in a number of manufacturing processes. … It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments

    Mixtures: Calcium Mg and Zn Capsules With Vitamin D, Infinitek Paris Broad Spectrum SPF 50 SunscreenCategories: Compounds used in a research, industrial, or household setting
  6. Target

    14-3-3 protein beta/alpha

    go.drugbank.com/bio_entities/BE0008974
    TargetHumans

    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding genera...

    Polypeptides: 14-3-3 protein beta/alpha
  7. Target

    UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase

    go.drugbank.com/bio_entities/BE0001512
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) (PubMed:12429098, PubMed:24460375).

    Polypeptides: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferaseSynonyms: UDP-4-amino-4-deoxy-L-arabinose aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase
  8. Pathway

    Acylcarnitine 3-methylbut-2-enoylcarnitine

    smpdb.ca/view/SMP0123330
    Metabolic

    3-methylbut-2-enoylcarnitine is an acylcarnitine. … Once in the matrix, 3-methylbut-2-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form 3-methylbut-2-enoyl-CoA and L-carnitine

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  9. Pathway

    Acylcarnitine 2-hydroxy-3-methylbutanedioylcarnitine

    smpdb.ca/view/SMP0123824
    Metabolic

    2-hydroxy-3-methylbutanedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 2-hydroxy-3-methylbutanedioyl-CoA reacts with L-carnitine to form 2-hydroxy-3-methylbutanedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  10. Pathway

    Acylcarnitine 3-Hydroxydodec-2-enedioylcarnitine

    smpdb.ca/view/SMP0124029
    Metabolic

    3-Hydroxydodec-2-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 3-hydroxydodec-2-enedioyl-CoA reacts with L-carnitine to form 3-hydroxydodec-2-enedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial