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Cefradine
go.drugbank.com/drugs/DB01333ApprovedWithdrawnA semi-synthetic cephalosporin antibiotic.
Synonyms: (6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, (6R,7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidCategories: MATE 1 Substrates, Cytochrome P-450 CYP3A InducersNitroprusside
go.drugbank.com/drugs/DB00325ApprovedInvestigationalNitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). … Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Categories: Compounds used in a research, industrial, or household settingProducts: NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE, Nitroprussid-Natrium AFTPharm 50 mg/2 ml InfusionslösungBrivaracetam
go.drugbank.com/drugs/DB05541ApprovedInvestigationalBrivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam [A19184].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: BRIVIACT®10 MG, BRIVIACT® 10 MG/ML SOLUCIÓN ORALEvolocumab
go.drugbank.com/drugs/DB09303ApprovedInvestigationalEvolocumab is designed to bind to PCSK9 and inhibit PCSK9 from binding to LDL receptors on the liver surface, resulting in more LDL receptors on the surface of the liver to remove LDL-C from the blood. … Evolocumab is a human IgG2 monoclonal antibody that targets the proprotein convertase subtilisin/kexin type 9 (PCSK9).
Products: REPATHA® 140 MG/ML, REPATHA 140 MG/ML SC ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADETZinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approved[A27280, L2082] Interestingly, zinc supplementation has become a critical intervention for treating diarrheal episodes in children. … It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
Mixtures: AVi VITAMIN C 1000 mg with Zinc, Real Ginger, Honey, Lemon and Lemongrass, FERROZINC - G SURUP, 100 MLProducts: Zink Aguettant 1 mg/ml Konzentrat zur Herstellung einer Infusionslösung, ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusionMitoxantrone
go.drugbank.com/drugs/DB01204ApprovedInvestigationalAn anthracenedione-derived antineoplastic agent.
Synonyms: 1,4-Bis(2-(2-hydroxyethylamino)ethyl)amino)-5,8-dihydroxyanthraquinoneCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic IndexTestosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalThe majority of the prescriptions written were for injectable (66%) and topical (32%) testosterone products. As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' … s Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector [L4659].
Mixtures: NOFERTYL® INYECTABLECategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesGlucose-6-phosphate Dehydrogenase Deficiency
smpdb.ca/view/SMP0000518DiseaseGlucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose phosphate pathway. G6PD converts glucose-6-phosphate into 6-phosphoglucono-delta-lactone. … Glucose-6-phosphate dehydrogenase deficiency, also called G6PDD, is a very common inherited inborn error of metabolism (IEM) that is characterized by a defect in the glucose-6-phosphate dehydrogenase gene
Drugs: Adenosine phosphate · ATP · Magnesium cation · Iron · 5-O-phosphono-alpha-D-ribofuranosyl diphosphate · D-glyceraldehyde 3-phosphate +4 moreEnzymes: 6-phosphogluconolactonase, Glucose-6-phosphate isomeraseAcylcarnitine 6-hydroxynon-5-enoylcarnitine
smpdb.ca/view/SMP0123424Metabolic6-hydroxynon-5-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 6-hydroxynon-5-enoyl-CoA reacts with L-carnitine to form 6-hydroxynon-5-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcylcarnitine 5-Hydroxydec-6-enoylcarnitine
smpdb.ca/view/SMP0123870Metabolic5-Hydroxydec-6-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydec-6-enoyl-CoA reacts with L-carnitine to form 5-hydroxydec-6-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more