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Sparsentan
go.drugbank.com/drugs/DB12548ApprovedInvestigational>A</sub>R and 0.8 nM for AT<sub>1</sub>R). … Sparsentan is a dual antagonist of the endothelin type A receptor (ET<sub>A</sub>R) and the angiotensin II (Ang II) type 1 receptor (AT<sub>1</sub>R) with a similar affinity for both (9.3 nM for ET<sub
Categories: Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA)Calcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt is a salt that is solid at room temperature, and it behaves as a typical ionic halide. … Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent.
Mixtures: PERI SOLUTION A, DIANEAL AL 2.5%Polysilicone-15
go.drugbank.com/drugs/DB11271ApprovedIt is the first polymeric UVB filer consisting of chromophores attached to a silicone backbone [L2796, L2797, L2799, F87, F88, F89]. … Polysilicone-15 is a silicone based UVB absorber [L2796, L2797, L2799, F87, F88, F89].
Mixtures: Derma Pella Sunscreen Advance Cream-GelCupric oxide
go.drugbank.com/drugs/DB11134ApprovedCupric oxide is used as a precursor in many copper-containing products such as wood preservatives and ceramics. … Cupric oxide may be found in over-the-counter vitamin-mineral supplements as a source of [DB09130]. The mean daily dietary intake of copper in adults ranges between 0.9 and 2.2 mg [L2422].
Mixtures: Vinate AZ, Niaacinamide Azelaic AC TURMER FA B6 Zinc Ox CopperIron
go.drugbank.com/drugs/DB01592ApprovedInvestigationalA metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems.
Mixtures: Ganilia Soft Gel, Vinate AZProducts: COMPLEJO DE HIDROXIDO DE HIERRO EN SACAROSA EQUIVALENTE A 100 MG DE HIERRO ELEMENTAL INYECTABLEClofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. … Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand.
Categories: OCT2 Substrates with a Narrow Therapeutic Index, OAT3/SLC22A8 Substrates with a Narrow Therapeutic IndexSynonyms: Cl-F-Ara-ASodium ferric gluconate complex
go.drugbank.com/drugs/DB09517ApprovedThe stable macromolecular complex is negatively charged at alkaline pH with an apparent molecular weight of 289,000 – 440,000 daltons on gel chromatography. … It is composed of iron (III) oxide hydrate directly bonded to sucrose with a chelating gluconate function in a molar ratio of two iron molecules to one gluconate.
Gelatin
go.drugbank.com/drugs/DB11242ApprovedInvestigationalVet approvedWithdrawnhigh level of gel strength and viscosity. … Gelatin is a multifunctional ingredient that is used in foods, pharmaceuticals, cosmetics, and photographic films as a gelling agent, stabilizer, thickener, emulsifier, as well as film former.
Mixtures: Cleanse Gut And ColonAdalimumab
go.drugbank.com/drugs/DB00051ApprovedInvestigationalA biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available.[L45643,L45818]. … It is produced by recombinant DNA technology using a mammalian cell expression system.
Products: HUMIRA® ACEprosartan
go.drugbank.com/drugs/DB00876ApprovedInvestigationalEprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Mixtures: EPROSARTAN RAT COM600/12.5, EPROSARTAN RAT COM600/12.5Products: EPROSARTAN - CT 600MG FILM