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Diphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalAs a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties. … Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies,
Synonyms: N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine, 2-(benzhydryloxy)-N,N-dimethylethylamineInternational brands: Dormarex 2Potassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnA white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
Mixtures: B S S STERILE IRRIGATING SOLUTION, Isolyte SInternational brands: Slow-K, Micro-KAdenosylhomocysteinase
go.drugbank.com/bio_entities/BE0001684TargetHumansCatalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (PubMed:10933798). Binds copper ions (By similarity)
Synonyms: S-adenosyl-L-homocysteine hydrolaseCytosol aminopeptidase
go.drugbank.com/bio_entities/BE0003882TargetHumansFor instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. … Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status
Synonyms: Peptidase S, Cysteinylglycine-S-conjugate dipeptidaseComplement C1s subcomponent
go.drugbank.com/bio_entities/BE0001529TargetEnzymeHumansComponent of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the ...
Synonyms: Complement component 1 subcomponent sGlyceraldehyde-3-phosphate dehydrogenase
go.drugbank.com/bio_entities/BE0000542TargetHumansNuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity)
Synonyms: Peptidyl-cysteine S-nitrosylase GAPDHDiclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approvedDiclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes.
Synonyms: [2-(2,6-dichloroanilino)phenyl]acetic acid, 2-((2,6-dichlorophenyl)amino)benzeneacetic acidMixtures: AFTOJEL % 0,1 + %3 JEL (5 G), Innoprax-5Mirdametinib
go.drugbank.com/drugs/DB07101ApprovedInvestigationalMirdametinib is a mitogen-activated protein kinase (MAP2K, MEK, MAPKK) inhibitor. On February 11, 2025, mirdametinib was approved by the FDA for the treatment of neurofibromatosis type 1 (NF1). … [A265065] Mirdametinib selectively and potently inhibits the MEK1/2 enzymes.[A265065]
Synonyms: (-)-N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE, N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE N-((2R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODOANILINO)BENZAMIDECategories: Mitogen-activated protein kinase (MEK) inhibitors, P-glycoprotein substratesAdenosylhomocysteinase
go.drugbank.com/bio_entities/BE0009225TargetPlasmodium falciparum (isolate 3D7)Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via
Synonyms: S-adenosyl-L-homocysteine hydrolase