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Displaying results 751 - 760 of 1993 in total
  1. Target

    Lysophosphatidic acid receptor 3

    go.drugbank.com/bio_entities/BE0020529
    TargetHumans

    Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer.

    Polypeptides: Lysophosphatidic acid receptor 3Synonyms: LPA receptor 3, Lysophosphatidic acid receptor Edg-7
  2. Drug

    Meprobamate

    go.drugbank.com/drugs/DB00371
    ApprovedIllicit

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) Meprobamate is a controlled substance in the U.S.

    Mixtures: 282 Mep Tab
  3. Drug

    Memantine

    go.drugbank.com/drugs/DB01043
    ApprovedInvestigational

    Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD).

    Categories: NMDA Receptor Antagonists, N-methyl-D-aspartate Receptor Antagonist
  4. Drug

    Esterified estrogens

    go.drugbank.com/drugs/DB09381
    Approved

    Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterifi...

  5. Target

    5-hydroxytryptamine receptor 4

    go.drugbank.com/bio_entities/BE0000084
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:10821780, PubMed:16102731, PubMed:35714614, PubMed

    Polypeptides: 5-hydroxytryptamine receptor 4Synonyms: Serotonin receptor 4
  6. Target

    B-cell receptor CD22

    go.drugbank.com/bio_entities/BE0000183
    TargetHumans

    Acts as an inhibitory coreceptor on the surface of B-cells and inhibits B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation.

    Polypeptides: B-cell receptor CD22Function: CD4 receptor binding
  7. Target

    Retinoic acid receptor beta

    go.drugbank.com/bio_entities/BE0000206
    TargetHumans

    Receptor for retinoic acid.

    Polypeptides: Retinoic acid receptor betaSynonyms: Nuclear receptor subfamily 1 group B member 2
  8. Target

    Muscarinic acetylcholine receptor M5

    go.drugbank.com/bio_entities/BE0000247
    TargetHumans

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M5Function: G protein-coupled acetylcholine receptor activity
  9. Target

    Alpha-2C adrenergic receptor

    go.drugbank.com/bio_entities/BE0000342
    TargetHumans

    Alpha-2 adrenergic receptors are G protein-coupled receptors for catecholamines that activate the G(i/o) protein pathway, thereby promoting adenylyl cyclase inhibition, ERK1/2 stimulation, and voltage-gated calcium channels suppression (...

    Polypeptides: Alpha-2C adrenergic receptorSynonyms: Alpha-2 adrenergic receptor subtype C4
  10. Target

    5-hydroxytryptamine receptor 2B

    go.drugbank.com/bio_entities/BE0000393
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:18703043, PubMed:23519210, PubMed:7926008, PubMed:8078486, PubMed:8143856, PubMed:8882600). … Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances (PubMed:12970106, PubMed:18703043, PubMed:23519210, PubMed:23519215, PubMed:24357322, PubMed:28129538, PubMed

    Polypeptides: 5-hydroxytryptamine receptor 2BSynonyms: Serotonin receptor 2B