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Displaying results 761 - 770 of 10000 in total
  1. Target

    Maleylacetoacetate isomerase

    go.drugbank.com/bio_entities/BE0000819
    TargetEnzymeHumans

    Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Also has low glutathione peroxidase activity with T-butyl and...

    Synonyms: Glutathione S-transferase zeta 1
  2. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0003776
    TargetMycobacterium tuberculosis

    May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

    Synonyms: S-adenosyl-L-homocysteine hydrolase
  3. Target

    Adenosine deaminase

    go.drugbank.com/bio_entities/BE0009226
    TargetPlasmodium falciparum (isolate 3D7)

    Catalyzes the hydrolytic deamination of adenosine to produce inosine (PubMed:19728741, PubMed:31002765). Unlike mammalian adenosine deaminases, also catalyzes the deamination of 5'-methylthioadenosine (MTA), a by-product of polyamine bio...

    Synonyms: S-methyl-5'-thioadenosine deaminase
  4. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. … [A233130] Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate
  5. Drug

    Lansoprazole

    go.drugbank.com/drugs/DB00448
    ApprovedInvestigational

    Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. … [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)

    Mixtures: DUOLANS 15/30 MG SR KAPSUL, 28 ADET, DUOLANS 30/30 MG SR KAPSUL, 28 ADETCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  6. Drug

    Bismuth subsalicylate

    go.drugbank.com/drugs/DB01294
    ApprovedVet approved

    [L32318] Bismuth subsalicylate is a component of HELIDAC Therapy (bismuth subsalicylate, [metronidazole], and [tetracycline]), which is a treatment regimen indicated for the eradication of _H. pylori_ … [A230728] It is an active ingredient found in Pepto-Bismol, a common over-the-counter medication that is used to temporarily treat discomforts of the stomach and gastrointestinal tract.

    Synonyms: 2-Hydroxy-benzo[1,3,2]dioxabismin-4-oneProducts: Sun Mark Stomach Relief, PEPTIMAX SR
  7. Drug

    Levodropropizine

    go.drugbank.com/drugs/DB12472
    Investigational

    Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).

    Mixtures: PULMOTUS 30 MG+ 2 MG/5 ML ŞURUP, 150 MLProducts: DROPOLEV-S 30 MG/5 ML ŞURUP, İSODOS 60 MG/5 ML ŞURUP, 1 ADET
  8. Target

    Cytochrome P450 2C9

    go.drugbank.com/bio_entities/BE0002793
    TargetEnzymeHumans

    Oxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol (PubMed:11950794). … Contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan (PubMed:25994031)

    Synonyms: (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase
  9. Drug

    Acyclovir

    go.drugbank.com/drugs/DB00787
    ApprovedInvestigational

    [L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. … Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis.

    Mixtures: HERPAZON % 5 + % 1 KREM, 5 GRAM, Activir Duo 50 mg/g + 10 mg/g CremeCategories: MATE 1 Substrates, MATE 2 Substrates
  10. Target

    Methionine synthase

    go.drugbank.com/bio_entities/BE0003310
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

    Synonyms: 5-methyltetrahydrofolate S-homocysteine methyltransferase