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Displaying results 761 - 770 of 10000 in total
  1. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. … [A233130] Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate
  2. Drug

    Phenformin

    go.drugbank.com/drugs/DB00914
    ApprovedWithdrawn

    A biguanide hypoglycemic agent with actions and uses similar to those of metformin. … Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries.

    Synonyms: β-PhenethybiguanideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  3. Target

    Spike glycoprotein

    go.drugbank.com/bio_entities/BE0010022
    TargetSARS-CoV-2

    The stalk domain of S contains three hinges, giving the head unexpected orientational freedom (PubMed:32817270).

    Synonyms: S glycoprotein
  4. Indication

    Inadequate response to sulfonylurea

    go.drugbank.com/conditions/DBCOND0106077
    Drugs: Metformin · Vildagliptin
  5. Drug

    Levodropropizine

    go.drugbank.com/drugs/DB12472
    Investigational

    Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).

    Mixtures: PULMOTUS 30 MG+ 2 MG/5 ML ŞURUP, 150 MLProducts: DROPOLEV-S 30 MG/5 ML ŞURUP, İSODOS 60 MG/5 ML ŞURUP, 1 ADET
  6. Drug

    Acyclovir

    go.drugbank.com/drugs/DB00787
    ApprovedInvestigational

    [L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. … Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis.

    Synonyms: 9-((2-hydroxyethoxy)methyl)guanineMixtures: HERPAZON % 5 + % 1 KREM, 5 GRAM, Activir Duo 50 mg/g + 10 mg/g Creme
  7. Target

    Protein S100-B

    go.drugbank.com/bio_entities/BE0001177
    TargetHumans

    Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain (PubMed:20950652, PubMed:6487634). Weakly binds calcium but binds zinc very tightly-di...

    Synonyms: S-100 protein beta chain, S-100 protein subunit beta
  8. Indication

    Staphylococcus aureus Infection

    go.drugbank.com/conditions/DBCOND0038243
    Drugs: Azithromycin · Clavulanic acid · Erythromycin · Light mineral oil
    Synonyms: Staphylococcus (S.) Aureus Infection
  9. Drug

    Troglitazone

    go.drugbank.com/drugs/DB00197
    ApprovedWithdrawn

    Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Substrates
  10. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Synonyms: 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide, 2,4-Diamino-6-piperidinopyrimidine 3-oxideMixtures: MINOXIDIL 7% / NIACINAMIDE 4% s, FluMisch 5% Minoxidil