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Glutathione S-transferase theta-2
go.drugbank.com/bio_entities/BE0004541TargetEnzymeHumansConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:1417752). Has a sulfatase activity (PubMed:1417752)
Polypeptides: Glutathione S-transferase theta-2Synonyms: GST class-theta-2Ephrin type-B receptor 2
go.drugbank.com/bio_entities/BE0004549TargetHumansInvolved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex.
Polypeptides: Ephrin type-B receptor 2Synonyms: EPH-like kinase 5Discoidin domain-containing receptor 2
go.drugbank.com/bio_entities/BE0004741TargetHumansTyrosine kinase involved in the regulation of tissues remodeling (PubMed:30449416). It functions as a cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration...
Polypeptides: Discoidin domain-containing receptor 2Synonyms: Discoidin domain receptor 2, Discoidin domain-containing receptor tyrosine kinase 2Calcium-dependent secretion activator 2
go.drugbank.com/bio_entities/BE0008710TargetHumansMay specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity)
Polypeptides: Calcium-dependent secretion activator 2Synonyms: CAPS-2, Calcium-dependent activator protein for secretion 2Death-associated protein kinase 2
go.drugbank.com/bio_entities/BE0009428TargetHumansCalcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depend...
Polypeptides: Death-associated protein kinase 2Synonyms: DAP kinase 2Homeodomain-interacting protein kinase 2
go.drugbank.com/bio_entities/BE0009447TargetHumansSerine/threonine-protein kinase involved in transcription regulation, p53/TP53-mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1/Brn3a and pro...
Polypeptides: Homeodomain-interacting protein kinase 2Interleukin-1 receptor-like 2
go.drugbank.com/bio_entities/BE0010198TargetHumansReceptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAP...
Polypeptides: Interleukin-1 receptor-like 2Synonyms: Interleukin-1 receptor-related protein 2NPC intracellular cholesterol transporter 2
go.drugbank.com/bio_entities/BE0010359TransporterHumansIntracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment (PubMed:11125141, PubMed:15937921, PubMed:17018531, PubMed:18772377, PubMed:295...
Polypeptides: NPC intracellular cholesterol transporter 2DNA polymerase subunit gamma-2
go.drugbank.com/bio_entities/BE0010885TargetHumansAccessory subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). Acts as an allosteric regulator of the holoenzyme activities. Enhances the polymerase activity and the processivity of POLG by inc...
Polypeptides: DNA polymerase subunit gamma-2Fructose-1,6-bisphosphatase isozyme 2
go.drugbank.com/bio_entities/BE0011215TargetEnzymeHumansCatalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate
Polypeptides: Fructose-1,6-bisphosphatase isozyme 2Synonyms: FBPase 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase 2