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Corticotropin-releasing hormone receptor 2
go.drugbank.com/bio_entities/BE0014244TargetHumansG protein-coupled receptor for CRH, UCN, UCN2 and UCN3 stress hormones, which plays a central role in whole body adaptation to stress (PubMed:11329063, PubMed:11416224, PubMed:20966082, PubMed:22689579, PubMed:32004470, PubMed:36335102)....
Polypeptides: Corticotropin-releasing hormone receptor 2Synonyms: CRFR-2, CRF-R-22-hydroxyacylsphingosine 1-beta-galactosyltransferase
go.drugbank.com/bio_entities/BE0015078EnzymeHumansCatalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system (PubMed...
Polypeptides: 2-hydroxyacylsphingosine 1-beta-galactosyltransferaseFatty-acid amide hydrolase 2
go.drugbank.com/bio_entities/BE0015331EnzymeHumansCatalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to thei...
Polypeptides: Fatty-acid amide hydrolase 2Synonyms: Oleamide hydrolase 2, Anandamide amidohydrolase 2Sodium/myo-inositol cotransporter 2
go.drugbank.com/bio_entities/BE0017647TransporterHumansInvolved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1 (PubMed:15172003, PubMed:19032932).
Polypeptides: Sodium/myo-inositol cotransporter 2Synonyms: Solute carrier family 5 member 11, Na(+)/myo-inositol cotransporter 2Mitochondrial amidoxime reducing component 2
go.drugbank.com/bio_entities/BE0017987EnzymeHumansCatalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed:21029045, PubMed:24423752). As a component of prodrug-converting system, reduc...
Polypeptides: Mitochondrial amidoxime reducing component 2Synonyms: MOSC domain-containing protein 2, Moco sulfurase C-terminal domain-containing protein 2Bcl-2-like protein 10
go.drugbank.com/bio_entities/BE0019838TargetHumansUnder apoptotic stress conditions, dissociates from ITPR1 and is displaced from mitochondria-associated endoplasmic reticulum membranes, leading to increased Ca(2+) transfer to mitochondria which promotes
Polypeptides: Bcl-2-like protein 10SUMO-activating enzyme subunit 2
go.drugbank.com/bio_entities/BE0020840TargetHumansThe heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine...
Polypeptides: SUMO-activating enzyme subunit 2Synonyms: Ubiquitin-like modifier-activating enzyme 2Diphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalWhen diphenoxylate is used alone, it is classified as a Schedule II. … This medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug Administration (FDA) and the DEA in the United States when used in preparations.
Synonyms: Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate, 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl esterMixtures: LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML, LAMDOTIL®Obinutuzumab
go.drugbank.com/drugs/DB08935ApprovedInvestigationalObinutuzumab is a humanized anti-CD20 monoclonal antibody designed to treat B-cell malignancies. … [L54521] Like other drugs in its class, obinutuzumab targets the CD20 antigen expressed on the surface of pre-B and mature B lymphocytes, mediating B-cell lysis.
Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: GAZYVA ® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN 1000 MG / VIAL 40 ML, GAZYVA 1000 MG IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADETDe Novo Triacylglycerol Biosynthesis TG(18:2(9Z,12Z)/22:5(7Z,10Z,13Z,16Z,19Z)/20:5(5Z,8Z,11Z,14Z,17Z))
smpdb.ca/view/SMP0024409MetabolicThe enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone