Search

Displaying results 781 - 790 of 10000 in total
  1. Target

    Anamorsin homolog

    go.drugbank.com/bio_entities/BE0009259
    TargetPlasmodium falciparum (isolate 3D7)

    Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. … Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.

    Synonyms: Fe-S cluster assembly protein DRE2 homolog
  2. Drug

    Ostrea edulis shell

    go.drugbank.com/drugs/DB14251
    Investigational

    Ostrea edulis shell is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: European Flat Oyster Shell
  3. Indication

    Adult Onset Still's Disease

    go.drugbank.com/conditions/DBCOND0136303
    Drugs: Canakinumab
    Synonyms: Adult-Onset Still´s Disease
  4. Target

    Laminin subunit alpha-1

    go.drugbank.com/bio_entities/BE0002108
    TargetHumans

    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. As a li...

    Synonyms: S-LAM alpha, S-laminin subunit alpha
  5. Drug

    Clobetasol propionate

    go.drugbank.com/drugs/DB01013
    ApprovedInvestigational

    Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.

    Synonyms: Clobetasol propionate E, 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionateInternational brands: Embeline E
  6. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0001684
    TargetHumans

    Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (PubMed:10933798). Binds copper ions (By similarity)

    Synonyms: S-adenosyl-L-homocysteine hydrolase
  7. Target

    Glyceraldehyde-3-phosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0000542
    TargetHumans

    Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity)

    Synonyms: Peptidyl-cysteine S-nitrosylase GAPDH
  8. Indication

    Adrenal Cushing Syndrome

    go.drugbank.com/conditions/DBCOND0148294
    Drugs: Mitotane
    Synonyms: Cushing s Syndrome
  9. Target

    Cytosol aminopeptidase

    go.drugbank.com/bio_entities/BE0003882
    TargetHumans

    For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. … Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status

    Synonyms: Peptidase S, Cysteinylglycine-S-conjugate dipeptidase
  10. Drug

    Cholecalciferol

    go.drugbank.com/drugs/DB00169
    ApprovedInvestigationalNutraceutical

    Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689]. … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation

    Synonyms: Vitamin D 3, Vitamin D-3International brands: Delta-D, Micro-D