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Cilostazol Action Pathway
smpdb.ca/view/SMP0000263Drug actionCilostazol, also sold as Pletal, is a drug used to prevent platelet aggregation, specifically treating symptoms of intermittent claudication caused by peripheral artery disease as well as preventing strokes. Cilostazol is ingested orally...
Dipyridamole (Antiplatelet) Action Pathway
smpdb.ca/view/SMP0000264Drug actionDipyridamole (also known as Persantine) can bind and inhibit cAMP-specific 3',5'-cyclic phosphodiesterase 4D at platelet cell, which prevent the release of arachidonic acid form membrane phospholipids that eventually decreasing thromboxa...
Acenocoumarol Action Pathway
smpdb.ca/view/SMP0000269Drug actionAcenocoumarol (also known as Nitrowarfarin or Sinthrome) is an anticoagulant that inhibit the liver enzyme vitamin K reductase, which cause Vitamin K1 2,3-epoxide could not be catalyzed by vitamin K reductase to form vitamin KH2, the red...
Dicumarol Action Pathway
smpdb.ca/view/SMP0000270Drug actionDicumarol (also known as bishydroxycoumarin) is an anticoagulant that inhibit the liver enzyme vitamin K reductase, which cause Vitamin K1 2,3-epoxide could not be catalyzed by vitamin K reductase to form vitamin KH2, the reduced form of...
Enoxaparin.
smpdb.ca/view/SMP0000272Drug actionEnoxaparin is a low molecular weight heparin used to reduce cardiovascular events. Enoxaparin's action is antithrombin-dependent. The drug binds to antithrombin III to reduce thrombin inhibition in the plasma. The drug increases the inac...
Ardeparin Action Pathway
smpdb.ca/view/SMP0000275Drug actionArdeparin, trade name Normiflo, is low molecular weight heparin with anticoagulant effects used to prevent thrombosis. Ardeparin binds and increases antithrombin III activity and inactivates thrombin, factor Xa and coagulation factors XI...
Ximelagatran Action Pathway
smpdb.ca/view/SMP0000279Drug actionXimelagatran is an anticoagulant drug used to prevent and treat blood clots, and was the first drug in the anticoagulant drug class to be able to be ingested orally. It was discontinued from distribution by its parent company AstraZeneca...
Streptokinase Action Pathway
smpdb.ca/view/SMP0000282Drug actionStreptokinase, or SK, is an enzyme and also a thrombolytic medication. We are focusing on the medication in this pathway, which is used to dissolve clots in patients experiencing heart attacks, or arterial/pulmonary embolisms. Streptokin...
Urokinase Action Pathway
smpdb.ca/view/SMP0000284Drug actionUrokinase is an enzyme that is part of the thrombolytics drug class, used to dissolve or break down blood clots. Urokinase activates plasminogen. Then zooming in even further to the endoplasmic reticulum within the liver, vitamin K1 2,3-...
Reteplase Action Pathway
smpdb.ca/view/SMP0000285Drug actionReteplase is an enzyme that is part of the thrombolytics drug class, used to dissolve or break down blood clots. Reteplase activates plasminogen. Then zooming in even further to the endoplasmic reticulum within the liver, vitamin K1 2,3-...