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Displaying results 71 - 80 of 1567 in total
  1. Pathway

    Lysinuric Protein Intolerance

    smpdb.ca/view/SMP0000197
    Disease

    Lysinuric protein intolerance (Hyperdibasic aminoaciduria II; Dibasic aminoaciduria II; Hyperdibasic aminoaciduria II; LPI), also called hyperdibasic aminoaciduria type 2 or familial protein intolerance, is an autosomal recessive metabol...

    Drugs: Cysteine · Potassium cation · Urea
    Enzymes: Chloride channel protein ClC-Ka, Sodium- and chloride-dependent transporter XTRP3
  2. Pathway

    Glucose Transporter Defect (SGLT2)

    smpdb.ca/view/SMP0000245
    Disease

    The major reabsorptive mechanism for D-glucose in the kidney is known to involve a lower affinity, high capacity Na()/glucose cotransporter, which is located in the early proximal convoluted tubule segment S1 and has a Na()-to-glucose co...

    Drugs: Cysteine · Potassium cation · Urea
    Enzymes: Chloride channel protein ClC-Ka, Sodium- and chloride-dependent transporter XTRP3
  3. Pathway

    Misoprostol Action Pathway

    smpdb.ca/view/SMP0124718
    Drug action

    Misoprostol is a prostaglandin E1 analog that reduces the risk of NSAID-induced gastric ulcers. Misoprostol is indicated as a tablet to reduce the risk of NSAID-induced gastric ulcers but not duodenal ulcers in high-risk patients. Misopr...

    Drugs: ATP · Misoprostol · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate +1 more
    Enzymes: Chloride anion exchanger, Potassium-transporting ATPase alpha chain 1
  4. Pathway

    Latanoprost Action Pathway

    smpdb.ca/view/SMP0175204
    Drug action

    Latanoprost is a prostaglandin E1 analog that reduces the risk of NSAID-induced gastric ulcers. Latanoprost stimulates prostaglandin receptors on parietal cells in the stomach to reduce gastric acid secretion. Latanoprost activates prost...

    Drugs: ATP · Latanoprost · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate +1 more
    Enzymes: Chloride anion exchanger, Potassium-transporting ATPase alpha chain 1
  5. Pathway

    Dinoprost tromethamine Action Pathway

    smpdb.ca/view/SMP0175205
    Drug action

    Dinoprost tromethamine is a prostaglandin E1 analog that reduces the risk of NSAID-induced gastric ulcers. Dinoprost tromethamine stimulates prostaglandin receptors on parietal cells in the stomach to reduce gastric acid secretion. Dinop...

    Drugs: ATP · Dinoprost tromethamine · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate +1 more
    Enzymes: Chloride anion exchanger, Potassium-transporting ATPase alpha chain 1
  6. Pathway

    Castor Oil Action Pathway

    smpdb.ca/view/SMP0174887
    Drug action

    Castor Oil is a prostaglandin E1 analog that reduces the risk of NSAID-induced gastric ulcers. Castor Oil stimulates prostaglandin receptors on parietal cells in the stomach to reduce gastric acid secretion. Castor Oil activates prostagl...

    Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid +1 more
    Enzymes: Chloride anion exchanger, Potassium-transporting ATPase alpha chain 1
  7. Pathway

    Latanoprostene bunod Action Pathway

    smpdb.ca/view/SMP0175202
    Drug action

    Latanoprostene bunod is a prostaglandin E1 analog that reduces the risk of NSAID-induced gastric ulcers. Latanoprostene bunod stimulates prostaglandin receptors on parietal cells in the stomach to reduce gastric acid secretion. Latanopro...

    Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid +1 more
    Enzymes: Chloride anion exchanger, Potassium-transporting ATPase alpha chain 1
  8. Pathway

    Tafluprost Action Pathway

    smpdb.ca/view/SMP0175201
    Drug action

    Tafluprost is a prostaglandin E1 analog that reduces the risk of NSAID-induced gastric ulcers. Tafluprost stimulates prostaglandin receptors on parietal cells in the stomach to reduce gastric acid secretion. Tafluprost activates prostagl...

    Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid +1 more
    Enzymes: Chloride anion exchanger, Potassium-transporting ATPase alpha chain 1
  9. Pathway

    Travoprost Action Pathway

    smpdb.ca/view/SMP0175203
    Drug action

    Travoprost is a prostaglandin E1 analog that reduces the risk of NSAID-induced gastric ulcers. Travoprost stimulates prostaglandin receptors on parietal cells in the stomach to reduce gastric acid secretion. Travoprost activates prostagl...

    Drugs: ATP · Travoprost · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate +1 more
    Enzymes: Chloride anion exchanger, Potassium-transporting ATPase alpha chain 1
  10. Pathway

    Lidocaine (Antiarrhythmic) Action Pathway

    smpdb.ca/view/SMP0000328
    Drug action

    potassium channel (I-Kur) open. … At rest, the cardiac cell membrane is impermeable to sodium and calcium ions, but is permeable to potassium ions via inward rectifier potassium channels (I-K1), which allow an outward flow of potassium

    Drugs: NADH · ATP · Lidocaine · Potassium cation · Calcium · Mesoheme +1 more
    Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4