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Dexchlorpheniramine maleate Drug Metabolism
smpdb.ca/view/SMP0130637MetabolicDexchlorpheniramine maleate passes through the liver and is then excreted from the body mainly through the kidney. … Dexchlorpheniramine maleate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Dexchlorpheniramine maleateArimoclomol
go.drugbank.com/drugs/DB05025ApprovedArimoclomol is a hydroxylamine derivative and a heat-shock protein-70 (HSP70) co-inducer. Arimoclomol was approved by the FDA on September 20, 2024, making it the first treatment for Niemann-Pick disease, type C (NPC). It is also being i...
Salts: Arimoclomol maleateCategories: MATE substrates, MATE 1 SubstratesSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
go.drugbank.com/bio_entities/BE0002254TargetHumansSDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity).
Synonyms: Malate dehydrogenase [quinone] iron-sulfur subunitGlasdegib
go.drugbank.com/drugs/DB11978ApprovedInvestigationalGlasdegib, also known as PF-04449913, is a small-molecule hedgehog signaling inhibitor selected under the group of benzimidazoles. In early research, benzimidazoles attracted large interest as they represented a class of inhibitors with ...
Salts: Glasdegib maleateCategories: MATE inhibitors, MATE 1 InhibitorsMidazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigationalMidazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in th...
Salts: Midazolam maleateMethotrimeprazine
go.drugbank.com/drugs/DB01403ApprovedA phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlo...
Salts: Methotrimeprazine maleateMaltase-glucoamylase
go.drugbank.com/bio_entities/BE0000837TargetEnzymeHumansAlpha-(1,4) exo-glucosidase involved in breakdown of dietary starch oligosaccharides in small intestine. Cleaves the non-reducing alpha-(1,4)-linked glucose residue in linear dextrins with retention of anomeric center stereochemistry (Pu...
Polypeptides: Maltase-glucoamylaseIrbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigationalIrbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy. It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected t...
Products: Enalapril MaleateDexchlorpheniramine maleate H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175046Drug actionDexchlorpheniramine maleate inhibits the H1 histamine receptor on blood vessel endothelial cells. … Dexchlorpheniramine maleate is a first generation H1-antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
Dexchlorpheniramine maleate H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175138Drug actionDexchlorpheniramine maleate is a first generation H1-antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.