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Glutamate receptor ionotropic, kainate 2
go.drugbank.com/bio_entities/BE0000826TargetHumansIonotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid (PubMed:7536611, PubMed:8730589, PubMed:14511640 … The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:14511640, PubMed:28180184, PubMed:34375587, PubMed:7536611, PubMed:8730589
Polypeptides: Glutamate receptor ionotropic, kainate 2Synonyms: Glutamate receptor 6, Excitatory amino acid receptor 4Glutamate receptor ionotropic, kainate 4
go.drugbank.com/bio_entities/BE0000827TargetHumansIonotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel. Cannot form functional channels on its own (PubMed:8263508).
Polypeptides: Glutamate receptor ionotropic, kainate 4Synonyms: Glutamate receptor KA-1, Excitatory amino acid receptor 1Glutamate receptor ionotropic, kainate 5
go.drugbank.com/bio_entities/BE0000828TargetHumansIonotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid.
Polypeptides: Glutamate receptor ionotropic, kainate 5Synonyms: Glutamate receptor KA-2, Excitatory amino acid receptor 2Receptor activity-modifying protein 1
go.drugbank.com/bio_entities/BE0000859TargetHumansAccessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed … Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA (PubMed:35324283, PubMed:38603770)
Polypeptides: Receptor activity-modifying protein 1Synonyms: Calcitonin-receptor-like receptor activity-modifying protein 1N-formyl peptide receptor 1
go.drugbank.com/bio_entities/BE0000995TargetHumansDifferential signaling is also defined by receptor oligomerization state. … Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis (PubMed:15210802).
Polypeptides: N-formyl peptide receptor 1Synonyms: fMLP receptor, fMet-Leu-Phe receptorAtrial natriuretic peptide receptor 2
go.drugbank.com/bio_entities/BE0000997TargetHumansReceptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth
Polypeptides: Atrial natriuretic peptide receptor 2Synonyms: Atrial natriuretic peptide receptor type BPeroxisome proliferator-activated receptor delta
go.drugbank.com/bio_entities/BE0001007TargetHumansOnce activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. … Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid.
Polypeptides: Peroxisome proliferator-activated receptor deltaSynonyms: Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2Trace amine-associated receptor 1
go.drugbank.com/bio_entities/BE0001044TargetHumansLigand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors (PubMed:31399635, PubMed:37935376 … Also functions as a receptor for various drugs and psychoactive substances, such as amphetamine and methamphetamine (PubMed:31399635, PubMed:37935376, PubMed:37935377).
Polypeptides: Trace amine-associated receptor 1Synonyms: Trace amine receptor 1Cytokine receptor common subunit gamma
go.drugbank.com/bio_entities/BE0002102TargetHumansCommon subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770)
Polypeptides: Cytokine receptor common subunit gammaSynonyms: IL-2 receptor subunit gamma, Interleukin-2 receptor subunit gammaCytokine receptor common subunit beta
go.drugbank.com/bio_entities/BE0002115TargetHumansActs by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA (PubMed:1495999). … Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells.
Polypeptides: Cytokine receptor common subunit betaSynonyms: GM-CSF/IL-3/IL-5 receptor common beta subunit