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Displaying results 791 - 800 of 10000 in total
  1. Drug

    Zoledronic acid

    go.drugbank.com/drugs/DB00399
    ApprovedInvestigational

    Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and [risedronic acid]. … [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.

    Salts: Zoledronate D,L-Lysine MonohydrateCategories: Heterocyclic Compounds, 1-Ring
  2. Target

    Hydroxymycolate synthase MmaA4

    go.drugbank.com/bio_entities/BE0003863
    TargetMycobacterium tuberculosis

    Probably transfers a methyl group from the S-adenosylmethionine (SAM) cofactor and, subsequently or simultaneously, a water molecule onto the double bound of ethylene substrates, leading to the formation

    Synonyms: S-adenosylmethionine-dependent methyltransferase
  3. Indication

    Primary Immune Deficiency Disorders (PIDD)

    go.drugbank.com/conditions/DBCOND0038807
    Drugs: Hyaluronidase (human recombinant)
    Synonyms: Primary Immunodeficiency Disease(s)
  4. Target

    Cyanocobalamin reductase / alkylcobalamin dealkylase

    go.drugbank.com/bio_entities/BE0002175
    TargetHumans

    Cobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and NADPH as cosubstrate (PubMed:187795...

    Synonyms: Alkylcobalamin:glutathione S-alkyltransferase
  5. Drug

    Amoxicillin

    go.drugbank.com/drugs/DB01060
    ApprovedInvestigationalVet approved

    Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.

    Mixtures: CLAMOXIN S, LUMOXBRON-SCategories: Penicillin G, Heterocyclic Compounds, 1-Ring
  6. Drug

    Hypochlorous acid

    go.drugbank.com/drugs/DB14135
    Investigational

    An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.

    Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Benzethonium

    go.drugbank.com/drugs/DB11125
    Approved

    There is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304]. … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments.

    Products: CLEAR S Suds, Careone Antimicrobial Foaming Hand Sp Falling Rain
  8. Target

    Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

    go.drugbank.com/bio_entities/BE0004448
    TargetHumans

    GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA (PubMed:15987998, PubMed:19417105, PubMed:2511002, PubMed:27863242). GS...

    Synonyms: G1 to S phase transition protein 1 homolog
  9. Drug

    Chlorhexidine

    go.drugbank.com/drugs/DB00878
    ApprovedInvestigationalVet approvedWithdrawn

    [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain. … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.

    Synonyms: N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide, 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)International brands: Prevacare R
  10. Target

    Peptidoglycan editing factor PgeF

    go.drugbank.com/bio_entities/BE0002757
    TargetEscherichia coli (strain K12)

    Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate (PubMed:31978345). Also has adenosine deaminase activity (PubMed:31978345).

    Synonyms: S-methyl-5'-thioadenosine phosphorylase, S-methyl-5'-thioadenosine phosphorylase YfiH