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Displaying results 801 - 810 of 10000 in total
  1. Target

    4-aminobutyrate aminotransferase GabT

    go.drugbank.com/bio_entities/BE0001510
    TargetEscherichia coli (strain K12)

    Pyridoxal phosphate-dependent enzyme that catalyzes transamination between primary amines and alpha-keto acids. Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semia...

    Synonyms: (S)-3-amino-2-methylpropionate transaminase
  2. Target

    Alcohol dehydrogenase class-3

    go.drugbank.com/bio_entities/BE0000009
    TargetEnzymeHumans

    Also acts as a S-nitroso-glutathione reductase by catalyzing the NADH-dependent reduction of S-nitrosoglutathione, thereby regulating protein S-nitrosylation (By similarity) … Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (PubMed:8460164).

    Synonyms: S-(hydroxymethyl)glutathione dehydrogenase
  3. Target

    Myosin regulatory light chain 12A

    go.drugbank.com/bio_entities/BE0004293
    TargetHumans

    Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)

    Synonyms: HEL-S-24
  4. Target

    2-Hydroxyacid oxidase 2

    go.drugbank.com/bio_entities/BE0004577
    TargetEnzymeHumans

    Oxidase that catalyzes the oxidation of medium and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, to the corresponding 2-oxoacids (PubMed:10777549). Its role in the oxidation of 2-hydroxy fatty acids may c...

    Synonyms: (S)-2-hydroxy-acid oxidase, peroxisomalFunction: (S)-2-hydroxy-acid oxidase activity
  5. Drug

    Titanium dioxide

    go.drugbank.com/drugs/DB09536
    Approved

    It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase. … Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium.

    Mixtures: Shiseido Ultimate Sun Protection S, Anthelios S - Ecran Solaire SPF 30Categories: Compounds used in a research, industrial, or household setting
  6. Target

    Nitric oxide synthase

    go.drugbank.com/bio_entities/BE0010197
    TargetEnzyme

    Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR … Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity).

    Synonyms: Peptidyl-cysteine S-nitrosylase NOS1, Peptidyl-cysteine S-nitrosylase NOS2
  7. Target

    Cyclopropane mycolic acid synthase 1

    go.drugbank.com/bio_entities/BE0003738
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.

    Synonyms: S-adenosylmethionine-dependent methyltransferase
  8. Drug

    Galantamine

    go.drugbank.com/drugs/DB00674
    ApprovedInvestigational

    As Alzheimer's disease is a progressive neurodegenerative disorder, galantamine is not known to alter the course of the underlying dementing process. … Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: ANTAMIN ® 8 MG, REMINYL ®ER CAPSULAS DE 8 MG
  9. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. … A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant.

    Mixtures: Adventure Medical Kits 1-4 Person First Aid, Polylab Surgical Spirit 98.8% v/vCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  10. Target

    Cyclopropane mycolic acid synthase 2

    go.drugbank.com/bio_entities/BE0001211
    TargetMycobacterium tuberculosis

    cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine

    Synonyms: S-adenosylmethionine-dependent methyltransferase