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Cytarabine
go.drugbank.com/drugs/DB00987ApprovedInvestigationalCytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. … A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 1-beta-D-Arabinofuranosylcytosine, cytosine-β-D-arabinofuranosideBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalBromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.
Mixtures: BRO-GU SOLUCION ORAL, BRO-GU SOLUCION ORALEtodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedIts therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. … Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties.
Products: LODINE CAPSULAS DE 300 MGSulfamethoxazole
go.drugbank.com/drugs/DB01015ApprovedInvestigational[L11830] In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial infections, including those of the urinary, respiratory, and gastrointestinal tracts. … Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria.
Mixtures: Nu-cotrimox-DS Tab 800/160mg, Nu-cotrimox Tab 400/80mgCategories: combinations of sulfonamides, Drugs for Treatment of TuberculosisZuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalZuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. … Known drug targets of zuclopenthixol include 5-hydroxytryptamine receptor 2A, D(1B) dopamine receptor, D(2) dopamine receptor, D(1A) dopamine receptor, and alpha-1A adrenergic receptor.
Categories: Dopamine D2 Receptor Antagonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeBenzylpenicillin
go.drugbank.com/drugs/DB01053ApprovedInvestigationalVet approvedIt is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. … Natural penicillins are considered the drugs of choice for several infections caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C and G streptococci
Mixtures: SENCAIN-S 100.000 IU/300.000 IU IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 FLAKON + 1 AMPUL, PROKAIN PENICILLIN 3.1.400.000 IU IM ENJEKSİYONLUK TOZ, 10 ADETCategories: combinations of penicillinsProcaine benzylpenicillin
go.drugbank.com/drugs/DB09320ApprovedVet approvedBenzylpenicillin is active against a wide range of organisms and is the drug of first choice for many infections. … It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts.
Mixtures: SENCAIN-S 100.000 IU/300.000 IU IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 FLAKON + 1 AMPUL, PROKAIN PENICILLIN 3.1.400.000 IU IM ENJEKSİYONLUK TOZ, 10 ADETCategories: combinations of penicillinsLacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigationalLacosamide exhibits a stereoselective mode of interaction with sodium channels. … Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents.
Products: Ag-lacosamideCabergoline
go.drugbank.com/drugs/DB00248ApprovedInvestigationalCabergoline possesses potent agonist activity on dopamine D2 receptors. … Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome.
Categories: Heterocyclic Compounds with 4 or More Rings, P-glycoprotein substrates with a Narrow Therapeutic IndexCarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigational[A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248] … Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982.
International brands: Paraplatin AQ, Paraplatin-AQCategories: Compounds used in a research, industrial, or household setting