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Displaying results 801 - 810 of 10000 in total
  1. Drug

    Interferon alfa

    go.drugbank.com/drugs/DB05258
    ApprovedInvestigationalWithdrawn

    Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. … Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. Of these, IFN-α2 and IFN-α14 are glycosylated.

    Synonyms: HuIFN-alpha-Le, IFN-αCategories: Interferon Type I, Cytochrome P-450 CYP1A2 Inhibitors
  2. Drug

    Nitazoxanide

    go.drugbank.com/drugs/DB00507
    ApprovedInvestigationalVet approved

    Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and … Recently, this drug has been studied as a broad-spectrum antiviral agent due to its ability to inhibit the replication of several RNA and DNA viruses [A31977].

    Categories: Heterocyclic Compounds, 1-RingProducts: N/a, XINPA 2 % POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL
  3. Indication

    Streptococcus Group A

    go.drugbank.com/conditions/DBCOND0032140
    Drugs: Mupirocin
    Synonyms: Group A streptococci, Group A Streptococcus
  4. Target

    Biliverdin reductase A

    go.drugbank.com/bio_entities/BE0000741
    TargetEnzymeHumans

    Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IXalpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor (PubMed:10858451, PubMed:7929092, PubMed:8424666,

    Polypeptides: Biliverdin reductase ASynonyms: BVR A
  5. Target

    Apolipoprotein A-II

    go.drugbank.com/bio_entities/BE0000922
    TargetHumans

    May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism

    Polypeptides: Apolipoprotein A-II
  6. Target

    Thromboxane-A synthase

    go.drugbank.com/bio_entities/BE0001893
    TargetHumans

    Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation (PubMed:11097184, PubMed:11297515, PubMed:22735388, … Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same

    Polypeptides: Thromboxane-A synthase
  7. Target

    Alpha-galactosidase A

    go.drugbank.com/bio_entities/BE0002422
    TargetEnzymeHumans

    Catalyzes the hydrolysis of glycosphingolipids and participates in their degradation in the lysosome

    Polypeptides: Alpha-galactosidase ASynonyms: Alpha-D-galactosidase A
  8. Target

    Surface protein A

    go.drugbank.com/bio_entities/BE0002809
    TargetNeisseria meningitidis

    Polypeptides: Surface protein A
  9. Target

    Apolipoprotein A-I

    go.drugbank.com/bio_entities/BE0003449
    CarrierTargetEnzymeHumans

    Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase

    Polypeptides: Apolipoprotein A-I
  10. Target

    Prelamin-A/C

    go.drugbank.com/bio_entities/BE0010877
    TargetHumans

    Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner … Lamin A and C also regulate matrix stiffness by conferring nuclear mechanical properties (PubMed:23990565, PubMed:25127216).

    Polypeptides: Prelamin-A/C