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Displaying results 8111 - 8120 of 8695 in total
  1. Drug

    Thioridazine

    go.drugbank.com/drugs/DB00679
    ApprovedWithdrawn

    A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimusc...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
  2. Drug

    Ritodrine

    go.drugbank.com/drugs/DB00867
    ApprovedWithdrawn

    Adrenergic beta-agonist used to control premature labor.

    Synonyms: p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcoholCategories: Adrenergic beta-2 Receptor Agonists
  3. Drug

    Oprelvekin

    go.drugbank.com/drugs/DB00038
    ApprovedInvestigationalWithdrawn

    Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology. With a molecular mass of approximately 19,000 daltons, the non-glycosyla...

  4. Drug

    Sargramostim

    go.drugbank.com/drugs/DB00020
    ApprovedInvestigational

    Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.

  5. Drug

    Benzoin resin

    go.drugbank.com/drugs/DB11222
    Approved

    Benzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus Styrax. There are two common kinds of benzoin, benzoin Siam and benzoin Sumatra, that are obtained from different species of the Styrax tre...

  6. Drug

    Dalfopristin

    go.drugbank.com/drugs/DB01764
    Approved

    Dalfopristin is a combination of two antibiotics (Dalfopristin and quinupristin) used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium. It is not effective against Enterococcus faecalis infections. Da...

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  7. Drug

    Nepafenac

    go.drugbank.com/drugs/DB06802
    ApprovedInvestigational

    Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.

  8. Drug

    Teniposide

    go.drugbank.com/drugs/DB00444
    ApprovedInvestigational

    Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and pr...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Substrates
  9. Drug

    Muromonab

    go.drugbank.com/drugs/DB00075
    ApprovedInvestigationalWithdrawn

    More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method.

    Categories: CD3 Receptor Antagonists
  10. Drug

    Amodiaquine

    go.drugbank.com/drugs/DB00613
    ApprovedInvestigational

    A 4-aminoquinoquinoline compound with anti-inflammatory properties.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates