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Displaying results 811 - 820 of 10000 in total
  1. Drug

    Acetaminophen

    go.drugbank.com/drugs/DB00316
    ApprovedInvestigational

    Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization … while this drug is taken or prescribed.

    Synonyms: N-acetyl-p-aminophenol, 4-acetamidophenolInternational brands: Dapa X-S, St. Joseph Fever Reducer
  2. Drug

    Navepegritide

    go.drugbank.com/drugs/DB17824
    ApprovedInvestigational

    [L56065] Navepegritide was approved by the US FDA in February 2026 for use in patients 2 years of age and older with achondroplasia with open epiphyses.[L56058,L56065] … [L56058,A275435] Navepegritide is a prodrug of active C-type natriuretic peptide (CNP) consisting of a CNP moiety transiently conjugated to two methoxy polyethylene glycol (mPEG) moieties via a proprietary

  3. Target

    Alcohol dehydrogenase class-3

    go.drugbank.com/bio_entities/BE0000009
    TargetEnzymeHumans

    Also acts as a S-nitroso-glutathione reductase by catalyzing the NADH-dependent reduction of S-nitrosoglutathione, thereby regulating protein S-nitrosylation (By similarity) … Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (PubMed:8460164).

    Synonyms: S-(hydroxymethyl)glutathione dehydrogenase
  4. Target

    Myosin regulatory light chain 12A

    go.drugbank.com/bio_entities/BE0004293
    TargetHumans

    Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)

    Synonyms: HEL-S-24
  5. Drug

    Gabapentin

    go.drugbank.com/drugs/DB00996
    ApprovedInvestigational

    [L8717] It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic pain. … [A14097,A186179] Gabapentin has some stark advantages as compared with other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and lack of appreciable metabolism

    Synonyms: 1-(Aminomethyl)cyclohexaneacetic acidMixtures: Innoprax-5, GAVINDO N
  6. Pathway

    Cystathionine beta-Synthase Deficiency

    smpdb.ca/view/SMP0000177
    Disease

    Cystathionine Beta-Synthase Deficiency (CBS Deficiency; Homocystinuria) is an autosomal recessive disease caused by a mutation in the CBS gene which codes for cystathionine beta-synthase. A deficiency in this enzyme results in accumulati...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
    Enzymes: S-adenosylmethionine decarboxylase proenzyme, S-methyl-5'-thioadenosine phosphorylase
  7. Pathway

    Methionine Adenosyltransferase Deficiency

    smpdb.ca/view/SMP0000221
    Disease

    Methionine adenosyltransferase (MAT; Hypermethioninemia; MAT I/III deficiency) deficiency is caused by mutations in the MAT1A gene which causes isolated hypermethioninemia. MAT catalyzes the formation of adenosylmethionine from methionin...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
    Enzymes: S-adenosylmethionine decarboxylase proenzyme, S-methyl-5'-thioadenosine phosphorylase
  8. Pathway

    Hypermethioninemia

    smpdb.ca/view/SMP0000341
    Disease

    This gene is responsible for Adenosylhomocysteinase, an enzyme which takes S-adenosyl homocysteine as input, and produces homocysteine as its output.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
    Enzymes: S-adenosylmethionine decarboxylase proenzyme, S-methyl-5'-thioadenosine phosphorylase
  9. Target

    2-Hydroxyacid oxidase 2

    go.drugbank.com/bio_entities/BE0004577
    TargetEnzymeHumans

    Oxidase that catalyzes the oxidation of medium and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, to the corresponding 2-oxoacids (PubMed:10777549). Its role in the oxidation of 2-hydroxy fatty acids may c...

    Synonyms: (S)-2-hydroxy-acid oxidase, peroxisomalFunction: (S)-2-hydroxy-acid oxidase activity
  10. Pathway

    Methionine Metabolism

    smpdb.ca/view/SMP0000033
    Metabolic

    in a methylated product plus S-adenosylhomocysteine, and the conversion of S-adenosylhomocysteine to produce the compounds homocysteine and adenosine. … These pathways have three common reactions with both pathways including the transformation of methionine to S-adenosylmethionine (SAM), the use of SAM in many different transmethylation reactions resulting

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
    Enzymes: S-adenosylmethionine decarboxylase proenzyme, S-methyl-5'-thioadenosine phosphorylase