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Varicella zoster vaccine (recombinant)
go.drugbank.com/drugs/DB13924ApprovedInvestigationalFurthermore, because Shingrix is an inactivated vaccine it can also be used to prevent shingles and PHN in individuals with suppressed immune systems, who are already at increased risk of developing shingles … First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing Zostavax as
Products: SHINGRIX POWDER AND SUSPENSION FOR SUSPENSION FOR INJECTION 50MCG/0.5MLDapagliflozin
go.drugbank.com/drugs/DB06292ApprovedInvestigational[A261601] Dapagliflozin was originally approved by the FDA on Jan 08, 2014, to improve glycemic control in adults with type 2 diabetes in conjunction with diet and exercise. … [A261596] When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron and causing glycosuria
Mixtures: XIGDUO XR TABLETS 5MG/500MG, XIGDUO®XR 5MG/1000MGCategories: Drugs Used in Diabetes, Alimentary Tract and MetabolismSelumetinib
go.drugbank.com/drugs/DB11689ApprovedInvestigationalNF-1 is considered rare, with an estimated incidence of 1/3000 individuals. … [A193608] Use of selumetinib in this population has shown efficacy in shrinking associated tumours and is linked to other positive clinical outcomes.
Categories: Antineoplastic and Immunomodulating AgentsProducts: KOSELUGO HARD CAPSULES 10MG, KOSELUGO HARD CAPSULES 25MGD-alpha-Tocopherol acetate
go.drugbank.com/drugs/DB14002ApprovedNutraceuticalVet approvedAlpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. … At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use.
Mixtures: Coen.q10w.vit.c and E Beta-car.se Cu Zn Mn, Vit E 400unit W Selenium 50mcgCategories: Diet, Food, and Nutrition, Compounds used in a research, industrial, or household settingEzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigationalthat NPC1L1 plays an essential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway. … [A15202] By interfering with the intestinal uptake of cholesterol and phytosterols, ezetimibe reduces the delivery of intestinal cholesterol to the liver.[L11347]
Mixtures: ATOZET TABLET 10MG/20MG, Atozet 10mg/20mg film-coated tabletsCategories: pravastatin and ezetimibe, simvastatin and ezetimibeCyproterone acetate
go.drugbank.com/drugs/DB04839ApprovedInvestigationalAn anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. … It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Mixtures: CLIMEN 2MG+ 2MG/1 MG KAPLI TABLET, 21 ADET, Alisma 2mg/35µg FilmtablettenCategories: Antiandrogens and Estrogens, cyproterone and estrogenNintedanib
go.drugbank.com/drugs/DB09079ApprovedInvestigationalNintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). … [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved for patients who have tried and failed first-line chemotherapeutic options.[L8459]
Categories: Antineoplastic and Immunomodulating AgentsProducts: OFEV SOFT CAPSULES 150MG, OFEV SOFT CAPSULES 100MGCtenocephalides felis
go.drugbank.com/drugs/DB10693ApprovedCat flea allergenic extract is used in allergenic testing.
Synonyms: cat flea allergenic extractProducts: Cat FleaHomocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
smpdb.ca/view/SMP0125684DiseaseSymptoms include megaloblastic anemia, and can also include developmental delays, seisures and kidney failure. Treatment with vitamin B12, as well as folates and betaine is effective. … Methionine synthase deficiency is characterized by an increase in homocysteine levels in the body and excreted in the urine, as well as decreased levels of methionine in the blood.
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 moreLong-Chain-3-Hydroxyacyl-CoA Dehydrogenase Deficiency (Fatty Acid Elongation in Mitochondria)
smpdb.ca/view/SMP0125748DiseaseSigns and symptoms of LCHAD deficiency typically manifest during infancy or early childhood and can include feeding difficulties, hypoglycemia, hypotonia, lethargy, liver problems, and retinal abnormalities … LCHAD-deficiency individuals are also at risk for breathing difficulties, serious heart problems, coma, and sudden death. Fasting or illnesses (e.g. viral infections) can trigger related problems.