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Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
go.drugbank.com/bio_entities/BE0004448TargetHumansGTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA (PubMed:15987998, PubMed:19417105, PubMed:2511002, PubMed:27863242). GS...
Synonyms: G1 to S phase transition protein 1 homologDiphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalAs a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties. … Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies,
Synonyms: N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine, 2-(benzhydryloxy)-N,N-dimethylethylamineInternational brands: Dormarex 2Tolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedTolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. … It is sold under several brand names, most notably Tinactin and Odor Eaters.
Mixtures: PERMUT®, เดอมิกซ์-4Synonyms: 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate, m,N-Dimethylthiocarbanilic acid O-2-naphthyl esterPeptidoglycan editing factor PgeF
go.drugbank.com/bio_entities/BE0002757TargetEscherichia coli (strain K12)Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate (PubMed:31978345). Also has adenosine deaminase activity (PubMed:31978345).
Synonyms: S-methyl-5'-thioadenosine phosphorylase, S-methyl-5'-thioadenosine phosphorylase YfiHTransitional endoplasmic reticulum ATPase
go.drugbank.com/bio_entities/BE0004572TargetHumansNecessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to...
Synonyms: HEL-S-70Galectin-2
go.drugbank.com/bio_entities/BE0003247TargetHumansThis protein binds beta-galactoside. Its physiological function is not yet known
Synonyms: S-Lac lectin 2Aldo-keto reductase family 1 member A1
go.drugbank.com/bio_entities/BE0004352TargetEnzymeHumansAlso acts as an inhibitor of protein S-nitrosylation by mediating degradation of S-nitroso-coenzyme A (S-nitroso-CoA), a cofactor required to S-nitrosylate proteins (PubMed:30538128). … Also acts as a S-nitroso-glutathione reductase by catalyzing the NADPH-dependent reduction of S-nitrosoglutathione (PubMed:31649033). Displays no reductase activity towards retinoids (By similarity)
Synonyms: S-nitroso-CoA reductasePrimary Immune Deficiency Disorders (PIDD)
go.drugbank.com/conditions/DBCOND0038807Synonyms: Primary Immunodeficiency Disease(s)Nitric oxide synthase, inducible
go.drugbank.com/bio_entities/BE0000005TargetEnzymeHumansAlso has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). … As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity
Synonyms: Peptidyl-cysteine S-nitrosylase NOS2ATP-binding cassette sub-family C member 1
go.drugbank.com/bio_entities/BE0000785TargetTransporterHumansExports S-geranylgeranyl-glutathione (GGG) in lymphoid cells and stromal compartments of lymphoid organs. … Mediates basolateral export of GSH-conjugated R- and S-prostaglandin A2 diastereomers in polarized epithelial cells (PubMed:9426231).
Synonyms: Glutathione-S-conjugate-translocating ATPase ABCC1Function: ABC-type glutathione S-conjugate transporter activity