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Displaying results 821 - 830 of 10000 in total
  1. Drug

    Cetylpyridinium

    go.drugbank.com/drugs/DB11073
    ApprovedInvestigational

    In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis. … Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays.

    Mixtures: BUCOSEPTOL N, Emercreme No4 Ont EfaCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  2. Drug

    Apixaban

    go.drugbank.com/drugs/DB06605
    ApprovedInvestigational

    It is marketed under the name Eliquis[Label,L6043]. Apixaban was approved by the FDA on December 28, 2012[L6043]. … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Nb-apixaban, Nb-apixaban Tablet
  3. Drug

    VO659

    go.drugbank.com/drugs/DB18160
    Investigational

    VO659 is an antisense oligonucleotide being investigated for the treatment of Huntington's disease.

    Synonyms: an antisense oligonucleotide that has been developed to target expanded CAG repeats in messenger ribonucleic acid (mRNA)
  4. Drug

    Amitriptyline

    go.drugbank.com/drugs/DB00321
    ApprovedInvestigational

    Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. … [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.[A174661]

    Mixtures: โพลีบอน 4-10, Etrafon 2 10Categories: Analgesics, Non-Narcotic, Non-Selective Monoamine Reuptake Inhibitors
  5. Indication

    Glioblastoma Multiforme (GBM)

    go.drugbank.com/conditions/DBCOND0046976
    Drugs: Nimotuzumab
    Synonyms: Glioblastoma, no ICD-O subtype, Glioblastoma, no International Classification of Diseases for Oncology subtype
  6. Drug

    Brimonidine

    go.drugbank.com/drugs/DB00484
    ApprovedInvestigational

    [A178948,A178969] Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. … [A178945] Thus brimonidine is an effective and safe alternative to beta-blockers, in patients with, or at high risk for, cardiopulmonary disease.

    Mixtures: NEFRIDAXEM B+D, Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4%Categories: Sympathomimetics in Glaucoma Therapy, Heterocyclic Compounds, 2-Ring
  7. Drug

    Bemotrizinol

    go.drugbank.com/drugs/DB11206
    Approved

    Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. … It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application [A19212, A32909].

    Mixtures: Dpc Pink Aura Cushion No.21, Dpc Pink Aura Cushion No.23Categories: Heterocyclic Compounds, 1-Ring
  8. Indication

    Carcinoid Tumors

    go.drugbank.com/conditions/DBCOND0030495
    Drugs: Pentetreotide
    Synonyms: Carcinoid tumour no ICD-O subtype, Carcinoid tumor no ICD-O subtype
  9. Indication

    Lymphomas

    go.drugbank.com/conditions/DBCOND0029770
    Drugs: Allopurinol · Betamethasone · Bupivacaine · Chlorambucil · Cortisone acetate · Cyclophosphamide +9 more
    Synonyms: Malignant lymphoma, no ICD-O subtype, Malignant lymphoma, no ICD-O subtype (morphologic abnormality)
  10. Drug

    Amiodarone

    go.drugbank.com/drugs/DB01118
    ApprovedInvestigational

    Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved for its approved indications, according to prescribing information.[L3561,L11265,L11286] … Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.

    Categories: Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexSynonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran, 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran