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Displaying results 821 - 830 of 7452 in total
  1. Drug

    Mannitol

    go.drugbank.com/drugs/DB00742
    ApprovedInvestigational

    On October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for … Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a

    Mixtures: Reveos Select CPD with AS-5 Red Cell Preservative Solution For Collection Of 500ml Of Blood, TERUFLEX Blood with Diversion Blood Sampling Arm Anticoagulant CPD with OPTISOL Red Cell Preservative for Collection of 450mL of BloodCategories: Drugs for Constipation, Compounds used in a research, industrial, or household setting
  2. Drug

    Raxtozinameran

    go.drugbank.com/drugs/DB18228
    ApprovedInvestigational

    Raxtozinameran is also known as Pfizer-BioNTech COVID-19 Vaccine and Comirnaty. It works by binding to the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which is a transmembrane glycoprotein that play...

    Synonyms: RNA (recombinant 5′-[1,2-[(3′-O-methyl)m7G-(5′→5′)-ppp-Am]]-capped all uridine→N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 spike glycoprotein secretory signal peptide
  3. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes. … [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling.

    Mixtures: ALLI-TRIPLECategories: Topical Products for Joint and Muscular Pain, Antiinflammatory Preparations, Non-Steroids for Topical Use
  4. Pathway

    Multiple Carboxylase Deficiency, Neonatal or Early Onset Form

    smpdb.ca/view/SMP0125778
    Disease

    The BTD gene encodes for biotinidase and the HLCS gene encodes for holocarboxylase synthetase. … Holocarboxylase synthetase deficiency also called Multiple Carboxylase Deficiency, Neonatal or Early Onset Form, is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of either mutations

    Drugs: Biotin · Lysine · ATP · Pyrophosphoric acid
  5. Target

    All-trans-retinol 13,14-reductase

    go.drugbank.com/bio_entities/BE0002320
    TargetHumans

    Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol. Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers.

    Polypeptides: All-trans-retinol 13,14-reductaseSynonyms: All-trans-13,14-dihydroretinol saturase
  6. Drug

    Gelatin

    go.drugbank.com/drugs/DB11242
    ApprovedInvestigationalVet approvedWithdrawn

    [L2110] The FDA withdrew its approval for the use of all intravenous drug products containing gelatin. Gelatin continues to be approved for other routes of administration.[L43942] … An increasing number of novel applications have been found for collagen and gelatin.[A32426] Gelatin is generally recognized as safe (GRAS) by the FDA to be a non-hazardous food or food ingredient.

    Mixtures: Gelaspan Solution for infusion
  7. Drug

    Metoclopramide

    go.drugbank.com/drugs/DB01233
    ApprovedInvestigational

    It is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures.

    Categories: Drugs for Functional Gastrointestinal DisordersProducts: Metoperan Solution for Injection 5mg/mL
  8. Indication

    Carcinoid Tumors

    go.drugbank.com/conditions/DBCOND0030495
    Drugs: Pentetreotide
    Synonyms: Carcinoid tumor no International Classification of Diseases for Oncology subtype
  9. Indication

    Lymphomas

    go.drugbank.com/conditions/DBCOND0029770
    Drugs: Betamethasone · Chlorambucil · Cortisone acetate · Cyclophosphamide · Dexamethasone · Hydrocortisone +6 more
    Synonyms: Malignant lymphoma, no International Classification of Diseases for Oncology subtype
  10. Target

    Glycogen phosphorylase, liver form

    go.drugbank.com/bio_entities/BE0000007
    TargetHumans

    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis

    Polypeptides: Glycogen phosphorylase, liver form