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Displaying results 821 - 830 of 2828 in total
  1. Drug

    Vaborbactam

    go.drugbank.com/drugs/DB12107
    ApprovedInvestigational

    Vaborbactam is a β-lactamase inhibitor based on a cyclic boronic acid pharmacophore. It has been used in trials investigating the treatment of bacterial infections in subjects with varying degrees of renal insufficiency. In August 2017, ...

  2. Drug

    Cladribine

    go.drugbank.com/drugs/DB00242
    ApprovedInvestigational

    Cladribine is a purine analogue or a chlorinated derivative of adenine that causes apoptosis of B and T lymphocytes. Cladribine was first approved in the United States in 1993 initially as a treatment for a number of hematological malign...

  3. Drug

    Ephedra sinica root

    go.drugbank.com/drugs/DB01363
    ApprovedNutraceutical

    Ephedra is an alkaloid chemical compound traditionally obtained from the plant Ephedra sinica. The sale of ephedra-containing supplements intended to increase muscle weight or promote weight loss was banned in the United States in 2004 d...

    Categories: Complex Mixtures
  4. Indication

    Herpes Simplex Infections

    go.drugbank.com/conditions/DBCOND0053830
    Drugs: Acyclovir · Foscarnet · Imiquimod
    Synonyms: Herpes simplex complex
  5. Target

    Solute carrier family 22 member 3

    go.drugbank.com/bio_entities/BE0003650
    TransporterHumans

    Mediates the bidirectional transport of polyamine agmatine (PubMed:12538837). Also transports guanidine (PubMed:10966924). Mediates the transport of choline (PubMed:40972734). … May contribute to regulate the transport of cationic compounds in testis across the blood-testis-barrier (Probable). Mediates the transport of polyamine spermidine and putrescine (By similarity).

    Synonyms: Organic cation transporter 3, Extraneuronal monoamine transporterFunction: choline transmembrane transporter activity
  6. Drug

    Tobramycin

    go.drugbank.com/drugs/DB00684
    ApprovedInvestigational

    Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is n...

  7. Drug

    SLx-4090

    go.drugbank.com/drugs/DB05678
    Investigational

    SLx-4090 is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes.

  8. Drug

    Cyanocobalamin

    go.drugbank.com/drugs/DB00115
    ApprovedInvestigationalNutraceutical

    Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt.

    Mixtures: Se-Natal, Se-Natal 19Categories: Vitamin B Complex
  9. Indication

    Hemophilia B

    go.drugbank.com/conditions/DBCOND0001612
    Drugs: Coagulation Factor IX (Recombinant) · Etranacogene dezaparvovec
    Synonyms: Sex-linked factor IX deficiency disease
  10. Drug

    Ampicillin

    go.drugbank.com/drugs/DB00415
    ApprovedInvestigationalVet approved

    Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.