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Complement C1q subcomponent subunit A
go.drugbank.com/bio_entities/BE0002094TargetHumansCore component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens … The C1Q subcomplex is activated by a hexamer of IgG complexed with antigens, while it is activated by a pentameric IgM (PubMed:19706439, PubMed:24626930, PubMed:29449492).
Polypeptides: Complement C1q subcomponent subunit AAmine oxidase [flavin-containing] A
go.drugbank.com/bio_entities/BE0002198TargetEnzymeHumansCatalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amin...
Polypeptides: Amine oxidase [flavin-containing] ASynonyms: MAO-A, Monoamine oxidase type AEndo-1,4-beta-xylanase A
go.drugbank.com/bio_entities/BE0002739TargetClostridium stercorariumEndoxylanase that degrades arabinoxylan and glucuronoxylan to xylobiose and xylotriose (in vitro).
Polypeptides: Endo-1,4-beta-xylanase ASynonyms: 1,4-beta-D-xylan xylanohydrolase AEndo-1,4-beta-xylanase A
go.drugbank.com/bio_entities/BE0003244TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Polypeptides: Endo-1,4-beta-xylanase ASynonyms: Xylanase A, 1,4-beta-D-xylan xylanohydrolase ADNA topoisomerase 4 subunit A
go.drugbank.com/bio_entities/BE0008383TargetStaphylococcus aureusPerforms the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit ANitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and … Recently, this drug has been studied as a broad-spectrum antiviral agent due to its ability to inhibit the replication of several RNA and DNA viruses [A31977].
Categories: Heterocyclic Compounds, 1-RingProducts: N/a, XINPA 2 % POLVO PARA RECONSTITUIR A SUSPENSIÓN ORALNeutral amino acid transporter A
go.drugbank.com/bio_entities/BE0000480TargetHumansInvolved in homeostasis of D-serine, a coagonist of synaptic NMDA receptors. … Displays sodium- and amino acid-dependent but uncoupled channel-like anion conductance with a preference SCN(-) > NO3(-) > I(-) > Cl(-) (PubMed:8910405)
Polypeptides: Neutral amino acid transporter AU1 small nuclear ribonucleoprotein A
go.drugbank.com/bio_entities/BE0002708TargetHumansIn a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs
Polypeptides: U1 small nuclear ribonucleoprotein ASynonyms: U1-A, U1 snRNP ADNA topoisomerase 4 subunit A
go.drugbank.com/bio_entities/BE0003726TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Performs the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit AMyocardin-related transcription factor A
go.drugbank.com/bio_entities/BE0004156TargetHumansTranscription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration (PubMed:26224645). The SR...
Polypeptides: Myocardin-related transcription factor ASynonyms: MRTF-A