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Displaying results 831 - 840 of 10000 in total
  1. Target

    2-Hydroxyacid oxidase 2

    go.drugbank.com/bio_entities/BE0004577
    TargetEnzymeHumans

    Oxidase that catalyzes the oxidation of medium and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, to the corresponding 2-oxoacids (PubMed:10777549). Its role in the oxidation of 2-hydroxy fatty acids may c...

    Synonyms: (S)-2-hydroxy-acid oxidase, peroxisomalFunction: (S)-2-hydroxy-acid oxidase activity
  2. Drug

    Titanium dioxide

    go.drugbank.com/drugs/DB09536
    Approved

    It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase. … Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium.

    Mixtures: Shiseido Ultimate Sun Protection S, Anthelios S - Ecran Solaire SPF 30Categories: Compounds used in a research, industrial, or household setting
  3. Target

    Nitric oxide synthase

    go.drugbank.com/bio_entities/BE0010197
    TargetEnzyme

    Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR … Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity).

    Synonyms: Peptidyl-cysteine S-nitrosylase NOS1, Peptidyl-cysteine S-nitrosylase NOS2
  4. Target

    Cyclopropane mycolic acid synthase 1

    go.drugbank.com/bio_entities/BE0003738
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.

    Synonyms: S-adenosylmethionine-dependent methyltransferase
  5. Drug

    Galantamine

    go.drugbank.com/drugs/DB00674
    ApprovedInvestigational

    As Alzheimer's disease is a progressive neurodegenerative disorder, galantamine is not known to alter the course of the underlying dementing process. … Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: ANTAMIN ® 8 MG, REMINYL ®ER CAPSULAS DE 8 MG
  6. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. … A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant.

    Mixtures: Adventure Medical Kits 1-4 Person First Aid, Polylab Surgical Spirit 98.8% v/vCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  7. Target

    Cyclopropane mycolic acid synthase 2

    go.drugbank.com/bio_entities/BE0001211
    TargetMycobacterium tuberculosis

    cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine

    Synonyms: S-adenosylmethionine-dependent methyltransferase
  8. Target

    Cyclopropane mycolic acid synthase 3

    go.drugbank.com/bio_entities/BE0002521
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cyclopropane ring at the proximal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.

    Synonyms: S-adenosylmethionine-dependent methyltransferase
  9. Target

    Neuronal Acetylcholine (nACh) Receptor Subunits

    go.drugbank.com/bio_entities/BE0009927
    TargetHumans

    by a collection of nAChR subunits. … Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability. nAChRs are excitatory neurotrasnmitter receptors formed

    Synonyms: nAChR7, NACHR alpha-10
  10. Drug

    Omeprazole

    go.drugbank.com/drugs/DB00338
    ApprovedInvestigationalVet approved

    Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].

    Mixtures: ORAZOLE ® 10 MG CAPSULACategories: P-glycoprotein inhibitors, P-glycoprotein substrates