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Allopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalThis disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals [A175942]. … It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677].
Synonyms: 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidineCategories: Heterocyclic Compounds, 2-RingTirofiban
go.drugbank.com/drugs/DB00775ApprovedInvestigationalTirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glyc...
Synonyms: (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid, N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosineProducts: TIROSTU 12.5 MG/50 ML IV KONSANTRE İNFÜZYONLUK ÇÖZELTİ, 1 ADET, AGRABAN 12.5 MG/50 ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 FLAKONTrimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approvedTrimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it … [L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of
Mixtures: SEPTRIN IV 5 ML 10 AMPUL, METOPRIM 800MG/160 MG FORT TABLET, 20 ADETCategories: MATE 2 Inhibitors, MATE 2 SubstratesDisopyramide
go.drugbank.com/drugs/DB00280ApprovedInvestigationalA class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar
Categories: Heterocyclic Compounds, 1-RingProducts: NORPACE 100 MG KAPSÜL, 25 ADET, NORPACE 100 MG KAPSÜL, 50 ADETEnsulizole
go.drugbank.com/drugs/DB11115ApprovedAccording to the FDA, the maximal approved concentration of ensulizole is 148 mM although concentrations ranging between 74 and 148mM can be found in commercial sunscreen products [A27151]. … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths.
Mixtures: Lovely Me EX 32900042, Easydew EG SUN Ultra ShieldCategories: Heterocyclic Compounds, 2-RingExenatide
go.drugbank.com/drugs/DB01276ApprovedInvestigationalExenatide was given FDA approval on April 28, 2005[L6106]. It is available as immediate- and extended-release formulations. … Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690].
Categories: Drugs Used in Diabetes, Glucagon-like peptide-1 (GLP-1) analoguesProducts: BYETTA 10 µG/40 µL SC KULLANIMA HAZIR DOLU ENJEKSİYON KALEMI ICINDE COZELTI, 2.4 ML (60 DOZ), BYETTA 5 µG/20 µL SC KULLANIMA HAZIR DOLU ENJEKSİYON KALEMI ICINDE COZELTI, 1.2 ML (60 DOZ)Warfarin
go.drugbank.com/drugs/DB00682ApprovedInvestigationalWarfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. … Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America.
Synonyms: 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarinCategories: Compounds used in a research, industrial, or household settingAvelumab
go.drugbank.com/drugs/DB11945ApprovedInvestigational[A261496] Avelumab was first approved by the FDA on March 23, 2017. … [A261496] On September 18 and December 18 of the same year, it was also granted approval by EMA [L48126] and Health Canada,[L48171] respectively.
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: BAVENCIO 200 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 FLAKON, BAVENCIO 200 mg/10mL concentrate for solution for infusionLiraglutide
go.drugbank.com/drugs/DB06655ApprovedInvestigational[A6932] Liraglutide was granted FDA approval on January 25, 2010.[L6070] … [A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining lysine residue at position 26 of the peptide precursor.
Synonyms: Arg34Lys26-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-GLP-1[7-37], N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptideMixtures: XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 10 ADET, XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADETErlotinib
go.drugbank.com/drugs/DB00530ApprovedInvestigationalErlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer … This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and other myeloproliferative disorders.
Synonyms: [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amineCategories: Heterocyclic Compounds, 2-Ring