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Methylmalonic aciduria type A protein, mitochondrial
go.drugbank.com/bio_entities/BE0000320TargetHumansPlays a dual role as both a protectase and a reactivase for MMUT (PubMed:21138732, PubMed:28943303). … Functions as a G protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT) (PubMed:20876572, PubMed:28497574).
Polypeptides: Methylmalonic aciduria type A protein, mitochondrialRibosomal small subunit pseudouridine synthase A
go.drugbank.com/bio_entities/BE0002034TargetEscherichia coli (strain K12)Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
Polypeptides: Ribosomal small subunit pseudouridine synthase ASynonyms: rRNA-uridine isomerase A, rRNA pseudouridylate synthase APeroxisomal acyl-coenzyme A oxidase 1
go.drugbank.com/bio_entities/BE0004135TargetEnzymeHumansMay play a role in peroxisomal beta-oxidation step in polyunsaturated fatty acids (PUFAs) biosynthesis. … Catalyzes the desaturation of fatty acyl-CoAs that have a saturated bond between C2 and C3 (2,3-saturated acyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs), and donates electrons directly to molecular
Polypeptides: Peroxisomal acyl-coenzyme A oxidase 1GABA(A) Receptor Benzodiazepine Binding Site
go.drugbank.com/bio_entities/BE0008668TargetHumansGABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit
Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Function: GABA-A receptor activity, GABA-A receptor activityMHC class I HLA-A protein
go.drugbank.com/bio_entities/BE0010186TargetHumansPolypeptides: MHC class I HLA-A proteinSynonyms: HLA-AHepatitis A virus cellular receptor 2
go.drugbank.com/bio_entities/BE0010551TargetHumansExpressed on natural killer (NK) cells and acts as a coreceptor to enhance IFN-gamma production in response to LGALS9 (PubMed:22323453).
Polypeptides: Hepatitis A virus cellular receptor 2Acyl-coenzyme A thioesterase 2, mitochondrial
go.drugbank.com/bio_entities/BE0013225EnzymeHumansCatalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:10944470, PubMed:16940157).
Polypeptides: Acyl-coenzyme A thioesterase 2, mitochondrialSynonyms: Acyl-coenzyme A thioester hydrolase 2aCinnamon oil
go.drugbank.com/drugs/DB15986ApprovedInvestigationalCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsProducts: Nwk A-FVL-lactate dehydrogenase A-like 6B
go.drugbank.com/bio_entities/BE0000100TargetHumansCatalyzes the interconversion of L-lactate and pyruvate with nicotinamide adenine dinucleotide NAD(+) as a coenzyme
Polypeptides: L-lactate dehydrogenase A-like 6BSerine/threonine-protein kinase A-Raf
go.drugbank.com/bio_entities/BE0000434TargetHumansInvolved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Phosphorylates PFKFB2 (PubMed:36402789)
Polypeptides: Serine/threonine-protein kinase A-RafSynonyms: Proto-oncogene A-Raf, Proto-oncogene A-Raf-1