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Cefdinir
go.drugbank.com/drugs/DB00535ApprovedInvestigationalCefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. … Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie.
Synonyms: (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino}-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acidInternational brands: Omnicef RGuanidine
go.drugbank.com/drugs/DB00536ApprovedIt is also used in laboratory research as a protein denaturant. … A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism.
Categories: MATE 1 Substrates, MATE 2 SubstratesCiprofloxacin
go.drugbank.com/drugs/DB00537ApprovedInvestigationalCiprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.
Mixtures: OTOFAST®, OQ-CORT®Categories: 4-Quinolones, MATE 1 InhibitorsNortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigationalNortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant (TCA). … [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.[L11881]
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamineBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: BENAZEPRIL E IDROCLOROTIAZIDE AUROBINDO, BENAZEPRIL E IDROCLOROTIAZIDE AUROBINDOCategories: Heterocyclic Compounds, 2-RingAmoxapine
go.drugbank.com/drugs/DB00543ApprovedAmoxapine, the <i>N</i>-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. … TCAs also block histamine H<sub>1</sub> receptors, α<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred
Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsSynonyms: 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepineFluorouracil
go.drugbank.com/drugs/DB00544ApprovedInvestigationalA pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Mixtures: Actikerall 5 mg/g + 100 mg/g Lösung zur Anwendung auf der Haut, VERRUTOL %0,5 + %10 DERİ ÇÖZELTİSİ (15 G)Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexPerflutren
go.drugbank.com/drugs/DB00556ApprovedInvestigationalPerflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane … During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.
Mixtures: Optison Perflutren Protein-Type A MicrospheresCategories: Compounds used in a research, industrial, or household settingBenzthiazide
go.drugbank.com/drugs/DB00562ApprovedBenzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). … Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide, 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxideSuccimer
go.drugbank.com/drugs/DB00566ApprovedInvestigationalA mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Categories: Compounds used in a research, industrial, or household settingSynonyms: DIM-SA, DMS-A