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Displaying results 851 - 860 of 10000 in total
  1. Drug

    Isopropyl alcohol

    go.drugbank.com/drugs/DB02325
    ApprovedInvestigational

    An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

    Mixtures: Sooth-a-Sting, Zylotrol-LCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Castor oil

    go.drugbank.com/drugs/DB11113
    ApprovedNutraceuticalVet approved

    [DB02955] has a hydroxyl group that provides a functional group location for various chemical reactions, making it a favourable substance in industrial applications [A31170]. … Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (_Ricinus communis_ L.) mainly cultivated in India, South America, Africa, and China.

    Mixtures: Polylab Surgical Spirit 98.8% v/v, HydroGold 9Products: De La Cruz Castor Oil, Well at Walgreens Castor Oil
  3. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results. … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose.

    Mixtures: L-Methyl MC NAC, L-Methyl-MC-NACCategories: Compounds used in a research, industrial, or household setting
  4. Indication

    Chronic Motor and Vocal Tic Disorder

    go.drugbank.com/conditions/DBCOND0082272
    Drugs: Aripiprazole · Pimozide
    Synonyms: Gilles de la Tourette, Gilles de La Tourette's Disease
  5. Target

    DNA gyrase subunit A

    go.drugbank.com/bio_entities/BE0000366
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.

    Polypeptides: DNA gyrase subunit A
  6. Target

    Leukotriene A-4 hydrolase

    go.drugbank.com/bio_entities/BE0001680
    TargetHumans

    Can utilize LTA5 less effectively as a substrate than LTA4, and produce LTB5 (PubMed:2996528). … addition to its pro-inflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro (PGP), a

    Polypeptides: Leukotriene A-4 hydrolaseSynonyms: Leukotriene A(4) hydrolase
  7. Target

    Acetyl-coenzyme A synthetase

    go.drugbank.com/bio_entities/BE0001916
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.

    Polypeptides: Acetyl-coenzyme A synthetase
  8. Target

    Nucleoside diphosphate kinase A

    go.drugbank.com/bio_entities/BE0003106
    TargetEnzymeHumans

    Catalyzes the transfer of a gamma-phosphoryl group from a nucleoside triphosphate, mainly ATP, to a nucleoside diphosphate via a ping-pong mechanism involving a phosphohistidine intermediate, therefore … May also function as a Mg(2+)-dependent 3'-5' DNA exonuclease, excising nucleotides from 3' single-stranded DNA or DNA with 3' single strand overhangs, suggesting a role in DNA nucleolytic processing (

    Polypeptides: Nucleoside diphosphate kinase ASynonyms: NDPK A, NDP kinase A
  9. Target

    Stringent starvation protein A

    go.drugbank.com/bio_entities/BE0003260
    TargetYersinia pestis

    Polypeptides: Stringent starvation protein ASynonyms: Putative stringent starvation protein A, Regulator of transcription stringent starvation protein A
  10. Target

    Poly(A) polymerase alpha

    go.drugbank.com/bio_entities/BE0004515
    TargetHumans

    May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus … Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites.

    Polypeptides: Poly(A) polymerase alpha