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Displaying results 851 - 860 of 10000 in total
  1. Target

    Serum amyloid A-1 protein

    go.drugbank.com/bio_entities/BE0004795
    TargetHumans

    Major acute phase protein

    Polypeptides: Serum amyloid A-1 protein
  2. Target

    Ephrin type-A receptor 3

    go.drugbank.com/bio_entities/BE0009437
    TargetHumans

    Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5 (By similarity). … Also activated by EFNA1, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development (PubMed:12794130). Involved in the retinotectal mapping of neurons.

    Polypeptides: Ephrin type-A receptor 3
  3. Target

    Ephrin type-A receptor 6

    go.drugbank.com/bio_entities/BE0009439
    TargetHumans

    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

    Polypeptides: Ephrin type-A receptor 6
  4. Target

    GABA-A gated chloride channel

    go.drugbank.com/bio_entities/BE0009556
    TargetOnchocerca volvulus

  5. Target

    ATP-dependent RNA helicase A

    go.drugbank.com/bio_entities/BE0014303
    TargetHumans

    Plays a role as a transcriptional coactivator acting as a bridging factor between polymerase II holoenzyme and transcription factors or cofactors, such as BRCA1, CREBBP, RELA and SMN1 (PubMed:11038348, … Plays a role in mRNA translation (PubMed:28355180).

    Polypeptides: ATP-dependent RNA helicase ASynonyms: RNA helicase A
  6. Drug

    Magnesium

    go.drugbank.com/drugs/DB14513
    ApprovedInvestigational

    [A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such as food processing and cooking vegetables (which are normally a rich source of magnesium).[A39559] … Magnesium is classified as an alkaline earth metal and has 2 hydration shells.

    Mixtures: Calcium Et Magnesium Plus Vitamine D/fe/zn, Fem - PmtProducts: EMGE 300MG PULV Z.HER E LO, MAGNEROT A 500 BEUTEL
  7. Drug

    Carmustine

    go.drugbank.com/drugs/DB00262
    ApprovedInvestigational

    (From Merck Index, 11th ed) … (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985).

    Synonyms: N,N'-Bis(2-chloroethyl)-N-nitrosoureaCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  8. Target

    Acetyl-coenzyme A synthetase, cytoplasmic

    go.drugbank.com/bio_entities/BE0000350
    TargetEnzymeHumans

    Can also utilize propionate with a much lower affinity (PubMed:38369012). Catalyzes the conversion of lactate into lactoyl-CoA (PubMed:39561764). … Acts as a chromatin-bound transcriptional coactivator that up-regulates histone acetylation and expression of neuronal genes (By similarity).

    Polypeptides: Acetyl-coenzyme A synthetase, cytoplasmic
  9. Target

    Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

    go.drugbank.com/bio_entities/BE0000377
    TargetHumans

    Plays a role in the maintenance of normal spermatogenesis through the reduction of fatty acid accumulation in the testes (By similarity) … Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion

    Polypeptides: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialSynonyms: Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase
  10. Target

    Ephrin type-A receptor 2

    go.drugbank.com/bio_entities/BE0000841
    TargetHumans

    With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis … May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration.

    Polypeptides: Ephrin type-A receptor 2