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Atigliflozin
go.drugbank.com/drugs/DB21394InvestigationalAtigliflozin is under investigation in clinical trial NCT00361738 (Dose-Ranging Study Evaluating AVE2268 in Patients With Type 2 Diabetes Not Adequately Controlled by a Metformin Treatment). … Atigliflozin is a small molecule drug.
Nitric oxide synthase 1
go.drugbank.com/bio_entities/BE0000067TargetEnzymeHumansProbably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR
Synonyms: Peptidyl-cysteine S-nitrosylase NOS14-aminobutyrate aminotransferase, mitochondrial
go.drugbank.com/bio_entities/BE0000253TargetEnzymeHumansCatalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively (PubMed:10407778, PubMed:15528998). Can also convert delta-aminovalerate and beta-alanine...
Synonyms: (S)-3-amino-2-methylpropionate transaminaseFunction: (S)-3-amino-2-methylpropionateCyclopropane mycolic acid synthase MmaA2
go.drugbank.com/bio_entities/BE0002512TargetMycobacterium tuberculosisCatalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.
Synonyms: S-adenosylmethionine-dependent methyltransferasePutative hydrolase DDAH2
go.drugbank.com/bio_entities/BE0000608TargetHumansPutative hydrolase with unknown substrate (Probable). Does not hydrolyze N(G),N(G)-dimethyl-L-arginine (ADMA) which acts as an inhibitor of NOS (PubMed:21493890, PubMed:37296100). In endothelial cells, induces expression of vascular endo...
Synonyms: S-phase proteinSuccinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
go.drugbank.com/bio_entities/BE0002256TargetEnzymeHumansKey enzyme for ketone body catabolism. Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate...
Synonyms: SCOT-sPrusogliptin
go.drugbank.com/drugs/DB20606InvestigationalPrusogliptin is under investigation in clinical trial NCT07026968 (A Study of Prusogliptin Tablets Combined With Dapagliflozin Tablets and Metformin Hydrochloride Extended Release Tablets in Type 2 Diabetes … Prusogliptin is a small molecule drug. The usage of the INN stem '-gliptin' in the name indicates that Prusogliptin is a dipeptidyl aminopeptidase-IV inhibitor.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 善泽平Aluminum zirconium octachlorohydrex gly
go.drugbank.com/drugs/DB11200ApprovedAluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent [L2705], [L2706].
Mixtures: Ron 2Products: Old Spice GentleMan s Blend Mandarin and Musk, Old Spice GentleMan s Blend Aloe and Wild SageKynurenine--oxoglutarate transaminase 1
go.drugbank.com/bio_entities/BE0000273TargetEnzymeHumansCatalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (PubMed:7883047)
Synonyms: Cysteine-S-conjugate beta-lyaseFunction: cysteine-S-conjugate beta-lyase activityHematopoietic prostaglandin D synthase
go.drugbank.com/bio_entities/BE0001167TargetHumansBifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide rang...
Synonyms: Glutathione S-transferase