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Heparan sulfate glucosamine 3-O-sulfotransferase 1
go.drugbank.com/bio_entities/BE0004436TargetHumansCatalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact) (PubMed:8900198, PubMed:9988768). … Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan (PubMed:8900198, PubMed:9346953, PubMed:9988768
Polypeptides: Heparan sulfate glucosamine 3-O-sulfotransferase 1Synonyms: Heparan sulfate 3-O-sulfotransferase 1, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1Catechol O-methyltransferase domain-containing protein 1
go.drugbank.com/bio_entities/BE0004586TargetHumansPutative O-methyltransferase
Polypeptides: Catechol O-methyltransferase domain-containing protein 1Function: O-methyltransferase activityCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigational[A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230] … Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of depression.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Combined Inhibitors of Serotonin/Norepinephrine ReuptakeProducts: CITALOPRAM DOC GENERICI, CITALOPRAM MYLAN GENERICSProtein-L-isoaspartate(D-aspartate) O-methyltransferase
go.drugbank.com/bio_entities/BE0001144TargetHumansrepair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in
Polypeptides: Protein-L-isoaspartate(D-aspartate) O-methyltransferaseCap-specific mRNA (nucleoside-2'-O-)-methyltransferase
go.drugbank.com/bio_entities/BE0001402TargetVACVInvolved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. … At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap.
Polypeptides: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferaseFunction: mRNA (nucleoside-2'-O-)-methyltransferase activityUDP-3-O-acyl-N-acetylglucosamine deacetylase
go.drugbank.com/bio_entities/BE0004110TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
Polypeptides: UDP-3-O-acyl-N-acetylglucosamine deacetylaseSynonyms: UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylaseBenzoyl peroxide
go.drugbank.com/drugs/DB09096ApprovedInvestigationalBenzoyl peroxide is a commonly used drug in topical treatments for acne. … [A234059,A234064,A234069] Benzoyl peroxide, in combination with erythromycin, was granted FDA approval on 26 October 1984.[L33264]
Synonyms: Peróxido de benzoiloMixtures: Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit, OXIMIN 10 MG/G + 50 MG/G JEL,50 GLinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigational] and, in doing so, prevents the formation of the 70S initiation complex which is essential for bacterial reproduction. … [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor.
Synonyms: N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamideCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesTolterodine
go.drugbank.com/drugs/DB01036ApprovedInvestigationalTolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Synonyms: (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMetamizole
go.drugbank.com/drugs/DB04817ApprovedInvestigationalWithdrawnMetamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. … [A251805] Metamizole is still used in certain countries in Europe, Asia and South America.[A251805]
Mixtures: DIPIRONA N- BULTILBROMURO DE HIOSCINA, N-BUTIL BROMURO DE HIOSCINA20MG + DIPIRONA 2500 MG/5 MLCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP3A Inducers