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Displaying results 8701 - 8710 of 10000 in total
  1. Drug

    Wortmannin

    go.drugbank.com/drugs/DB08059
    Experimental

    Wortmannin is a steroid metabolite of _Penicillium funiculosum_ and _Talaromyces wortmannii_ fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).

    Categories: Hormones, Hormone Substitutes, and Hormone Antagonists
  2. Drug

    Navamepent

    go.drugbank.com/drugs/DB21096
    Investigational

    Navamepent is under investigation in clinical trial NCT02329743 (Efficacy and Safety of RX-10045 Ophthalmic Solution for Ocular Inflammation and Pain in Cataract Surgery). … Navamepent is a small molecule drug.

  3. Drug

    Aderbasib

    go.drugbank.com/drugs/DB21288
    Investigational

    Aderbasib is under investigation in clinical trial NCT01254136 (Safety and Efficacy of INCB007839 With Trastuzumab and Vinorelbine in Patients With Metastatic HER2+ Breast Cancer). … Aderbasib is a small molecule drug.

  4. Drug

    AZD-1236

    go.drugbank.com/drugs/DB11961
    Investigational

    AZD1236 has been used in trials studying the basic science and treatment of Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.

  5. Drug

    Aticaprant

    go.drugbank.com/drugs/DB12341
    Investigational

    Aticaprant has been used in trials studying the health services research and basic science of Anxiety Disorders and Alcohol Dependence.

  6. Drug

    TBX-3400

    go.drugbank.com/drugs/DB17370
    Investigational

    TBX-3400 is an investigational cell-based immunotherapy consisting of autologous peripheral blood mononuclear cells (PBMCs) treated ex vivo with TBX-4000, which is a recombinant TAT-MYC fusion protein.

  7. Drug

    5'-Guanosine-Diphosphate-Monothiophosphate

    go.drugbank.com/drugs/DB01864
    Experimental

    A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  8. Target

    Atrial natriuretic peptide receptor 3

    go.drugbank.com/bio_entities/BE0002426
    TargetHumans

    May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. … Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production

    Synonyms: ANP-C
  9. Drug

    Testosterone enantate benzilic acid hydrazone

    go.drugbank.com/drugs/DB13947
    ApprovedWithdrawn

    Categories: Testosterone and derivatives, Hormones, Hormone Substitutes, and Hormone Antagonists
  10. Drug

    Tylosin

    go.drugbank.com/drugs/DB11475
    ExperimentalVet approved

    Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. … It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. Tylosin is produced as a fermentation product of Streptomyces fradiae.