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Displaying results 871 - 880 of 10000 in total
  1. Drug

    Thimerosal

    go.drugbank.com/drugs/DB11590
    Approved

    Although thimerosal is banned in several countries, it continues to be included as a preservative in some vaccines in the United States and many vaccines in the developing world [L1685]. … Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Dexbrompheniramine

    go.drugbank.com/drugs/DB00405
    Approved

    Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.

    Synonyms: 3-(4-bromophenyl)- N,N-dimethyl- 3-pyridin-2-yl-propan-1-amineMixtures: M-end Max D, M-end Dmx
  3. Drug

    Influenza A virus A/Christchurch/16/2010 NIB-74 (H1N1) antigen (propiolactone inactivated)

    go.drugbank.com/drugs/DB10781
    ApprovedWithdrawn

    Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.

    Mixtures: Physicians EZ Use Flu Kit, Medical Provider Single Use EZ Flu Shot Kit
  4. Drug

    Cisatracurium

    go.drugbank.com/drugs/DB00565
    ApprovedInvestigational

    [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. … Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.

  5. Drug

    Lanadelumab

    go.drugbank.com/drugs/DB14597
    ApprovedInvestigational

    [A38676] Lanadelumab was approved for use in patients with hereditary angioedema by the FDA in August 2018,[L4537] followed by Health Canada in October 2018[L49226] and the EMA in November 2018. … [L4538] It is a fully human immunoglobulin, k-light-chain made in recombinant Chinese Hamster Ovary cells.

    Categories: Drugs Used in Hereditary Angioedema
  6. Drug

    Tolbutamide

    go.drugbank.com/drugs/DB01124
    Approved

    Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. … The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. Tolbutamide appears to be metabolized in the liver.

    Synonyms: N-n-Butyl-N'-tosylurea, N-(Sulfonyl-p-methylbenzene)-N'-N-butylureaCategories: Drugs Used in Diabetes
  7. Drug

    Coal tar

    go.drugbank.com/drugs/DB11082
    Approved

    Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic arom...

    Mixtures: PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT, Multi-action Denorex 2-IN-1 Dandruff Shampoo + ConditionerProducts: Psoriasin In-Shower Treatment, COAL TAR SOLUTION 10% IN AQUEOUS CREAM
  8. Target

    Bile acid-CoA:amino acid N-acyltransferase

    go.drugbank.com/bio_entities/BE0002303
    TargetEnzymeHumans

    Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine (PubMed:12239217, PubMed:12810727, PubMed:2037576, PubMed:8034703). More than 95% of the BAs are N-acyl amidates with glycine and taurine (PubMed:803470...

    Synonyms: BACAT
  9. Drug

    Eprosartan

    go.drugbank.com/drugs/DB00876
    ApprovedInvestigational

    Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system.

    Synonyms: (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid, (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acidMixtures: EPROSARTAN E IDROCLOROTIAZIDE MYLAN, EPROSARTAN E IDROCLOROTIAZIDE MYLAN
  10. Drug

    Pegloticase

    go.drugbank.com/drugs/DB09208
    ApprovedInvestigational

    [L42425] Pegloticase was approved by the FDA in 2014, and in 2022, the drug label included the co-administration of pegloticase and methotrexate.[L42425] … [A249980] The PEG group also gives pegloticase a lower potential to induce an immune response.

    Categories: Compounds used in a research, industrial, or household setting