Search

Displaying results 871 - 880 of 10000 in total
  1. Indication

    Primary Immunoglobulin A Nephropathy (IgAN)

    go.drugbank.com/conditions/DBCOND0151924
    Drugs: Atacicept · Iptacopan · Sparsentan
    Synonyms: Primary Immunoglobulin A Nephropathy (IgAN)
  2. Indication

    Not a candidate for surgery

    go.drugbank.com/conditions/DBCOND0144299
    Drugs: Pembrolizumab · Spironolactone · Vimseltinib
    Synonyms: Not a candidate for surgery
  3. Indication

    HLA-A*02:06 positive

    go.drugbank.com/conditions/DBCOND0168342
    Drugs: Afamitresgene autoleucel
    Synonyms: HLA-A*02:06 positive
  4. Target

    L-lactate dehydrogenase A-like 6A

    go.drugbank.com/bio_entities/BE0000297
    TargetHumans

    Catalyzes the interconversion of L-lactate and pyruvate with nicotinamide adenine dinucleotide NAD(+) as a coenzyme (PubMed:18351441).

    Polypeptides: L-lactate dehydrogenase A-like 6A
  5. Target

    D-alanine--D-alanine ligase A

    go.drugbank.com/bio_entities/BE0000733
    TargetEscherichia coli (strain K12)

    Cell wall formation.

    Polypeptides: D-alanine--D-alanine ligase ASynonyms: D-Ala-D-Ala ligase A, D-alanylalanine synthetase A
  6. Target

    Peptidyl-prolyl cis-trans isomerase A

    go.drugbank.com/bio_entities/BE0001014
    TargetHumans

    Inhibits replication of influenza A virus (IAV) (PubMed:19207730). … Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (PubMed:11943775

    Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Rotamase A
  7. Target

    Ribosomal small subunit pseudouridine synthase A

    go.drugbank.com/bio_entities/BE0001276
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.

    Polypeptides: Ribosomal small subunit pseudouridine synthase ASynonyms: rRNA-uridine isomerase A, rRNA pseudouridylate synthase A
  8. Target

    Methane monooxygenase component A alpha chain

    go.drugbank.com/bio_entities/BE0003331
    TargetEnzymeMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)

    It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.

    Polypeptides: Methane monooxygenase component A alpha chain
  9. Target

    DNA polymerase epsilon catalytic subunit A

    go.drugbank.com/bio_entities/BE0003614
    TargetHumans

    Along with DNA polymerase POLD1 and DNA polymerase POLK, has a role in excision repair (NER) synthesis following UV irradiation (PubMed:20227374)

    Polypeptides: DNA polymerase epsilon catalytic subunit ASynonyms: DNA polymerase II subunit A
  10. Indication

    Prevention of subtype A viruses contained in the 2015 formula Influenza A Virus Infection

    go.drugbank.com/conditions/DBCOND0112773
    Drugs: Influenza A virus A/Slovenia/2903/2015 (H1N1) live (attenuated) antigen
    Synonyms: Prevention of subtype A viruses contained in the 2015 formula Influenza A Virus Infection