Search
Ribose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0003268TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase AEphrin type-A receptor 7
go.drugbank.com/bio_entities/BE0004140TargetHumansAmong GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. … May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity.
Polypeptides: Ephrin type-A receptor 7Acyl-coenzyme A thioesterase 13
go.drugbank.com/bio_entities/BE0004376TargetHumansMay play a role in controlling adaptive thermogenesis (By similarity) … Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16934754, PubMed:19170545).
Polypeptides: Acyl-coenzyme A thioesterase 13Ras-related protein Ral-A
go.drugbank.com/bio_entities/BE0004562TargetHumansMultifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. … Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling (PubMed:20005108).
Polypeptides: Ras-related protein Ral-ASerum amyloid A-1 protein
go.drugbank.com/bio_entities/BE0004795TargetHumansMajor acute phase protein
Polypeptides: Serum amyloid A-1 proteinEphrin type-A receptor 3
go.drugbank.com/bio_entities/BE0009437TargetHumansHighly promiscuous for ephrin-A ligands it binds preferentially EFNA5 (By similarity). … Also activated by EFNA1, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development (PubMed:12794130). Involved in the retinotectal mapping of neurons.
Polypeptides: Ephrin type-A receptor 3Ephrin type-A receptor 6
go.drugbank.com/bio_entities/BE0009439TargetHumansReceptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.
Polypeptides: Ephrin type-A receptor 6ATP-dependent RNA helicase A
go.drugbank.com/bio_entities/BE0014303TargetHumansPlays a role as a transcriptional coactivator acting as a bridging factor between polymerase II holoenzyme and transcription factors or cofactors, such as BRCA1, CREBBP, RELA and SMN1 (PubMed:11038348, … Plays a role in mRNA translation (PubMed:28355180).
Polypeptides: ATP-dependent RNA helicase ASynonyms: RNA helicase AAcetyl-coenzyme A synthetase, cytoplasmic
go.drugbank.com/bio_entities/BE0000350TargetEnzymeHumansCan also utilize propionate with a much lower affinity (PubMed:38369012). Catalyzes the conversion of lactate into lactoyl-CoA (PubMed:39561764). … Acts as a chromatin-bound transcriptional coactivator that up-regulates histone acetylation and expression of neuronal genes (By similarity).
Polypeptides: Acetyl-coenzyme A synthetase, cytoplasmic