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Displaying results 881 - 890 of 10000 in total
  1. Drug

    Hydrogenated soybean oil

    go.drugbank.com/drugs/DB11302
    Approved

    It may be found in cosmetics and personal care products as an emollient or skin conditioning agent. … Extracted from the seeds of the soybean (Glycine soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and salad and cooking oils.

    Products: S Balloon Slim Body Line
  2. Drug

    Tafluprost

    go.drugbank.com/drugs/DB08819
    Approved

    Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

    Mixtures: TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container, Taptiqom 15 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisProducts: TAFLOTAN-S ophthalmic solution 0.0015% (single-dose container), Saflutan 15 Mikrogramm/ml Augentropfen im Einzeldosisbehältnis
  3. Drug

    Panthenol

    go.drugbank.com/drugs/DB11204
    Approved

    Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.

    Mixtures: Foasu Jin Powderwash, Anbiser B-HA Hyaluronic Acid NourishingCategories: Vitamin B Complex
  4. Drug

    Sulfadiazine

    go.drugbank.com/drugs/DB00359
    ApprovedInvestigationalVet approved

    One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

    Mixtures: SUFATRIM 48%w/w Premix, TMP/S-400 Medicated Premix PowderCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  5. Drug

    Coagulation Factor IX (Recombinant)

    go.drugbank.com/drugs/DB00100
    Approved

    It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell … medium that is then processed and purified for use as a pharmaceutical agent.

    Synonyms: Recombinant factor IX, Factor IX (Recombinant)Products: BENEFIX 250 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADET, BENEFIX 500 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADET
  6. Drug

    Vincristine

    go.drugbank.com/drugs/DB00541
    ApprovedInvestigational

    Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. … It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar.

    Mixtures: MEODEX®, MEODEX®Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  7. Drug

    Nitroglycerin

    go.drugbank.com/drugs/DB00727
    ApprovedInvestigational

    Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in 1847. … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and prevent angina.[A249970] Nitroglycerin causes vasodilation in both arteries and veins.

    Mixtures: Nitroglycerin In 5% Dextrose Inj.-400mcg/ml, Nitroglycerin In 5% Dextrose Inj.-200mcg/mlCategories: Compounds used in a research, industrial, or household setting, Vasodilators Used in Cardiac Diseases
  8. Target

    Melanoma antigen preferentially expressed in tumors

    go.drugbank.com/bio_entities/BE0010493
    TargetHumans

    In the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role in chromstin … Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation (PubMed:21822215, PubMed:26138980

    Polypeptides: Melanoma antigen preferentially expressed in tumors
  9. Drug

    Aflibercept

    go.drugbank.com/drugs/DB08885
    ApprovedInvestigational

    [A261130] Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo Daltons (kDa). … [L47976] An aflibercept biosimilar, Yesafili, was approved for use in the EU in September 2023.

    Products: EYLEA SOLUTION FOR INJECTION IN VIAL 2MG, EYLEA 40MG/ML SOLUTION FOR INJECTION IN VIAL
  10. Drug

    Morphine

    go.drugbank.com/drugs/DB00295
    ApprovedInvestigational

    Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol, (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol