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Displaying results 881 - 890 of 6948 in total
  1. Target

    Endothelin-1 receptor

    go.drugbank.com/bio_entities/BE0000521
    TargetHumans

    Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

    Polypeptides: Endothelin-1 receptorSynonyms: Endothelin receptor type A
  2. Target

    Folate receptor gamma

    go.drugbank.com/bio_entities/BE0000652
    TargetHumans

    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate

    Polypeptides: Folate receptor gammaSynonyms: Folate receptor 3
  3. Target

    Dopamine receptor D2

    go.drugbank.com/bio_entities/BE0000756
    TargetHumans

    Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:40683247) … DRD2 can also couple with G(q) by forming a heteromer with the ghrelin receptor GHSR in neurons independently of ghrelin (By similarity).

    Polypeptides: Dopamine receptor D2Synonyms: Dopamine D2 receptor
  4. Target

    Glutamate receptor 4

    go.drugbank.com/bio_entities/BE0000830
    TargetHumans

    The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (By similarity). … Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic

    Polypeptides: Glutamate receptor 4Synonyms: AMPA-selective glutamate receptor 4, Glutamate receptor ionotropic, AMPA 4
  5. Target

    Succinate receptor 1

    go.drugbank.com/bio_entities/BE0002258
    TargetHumans

    G protein-coupled receptor for succinate able to mediate signaling through Gq/GNAQ or Gi/GNAI second messengers depending on the cell type and the processes regulated (By similarity) (PubMed:15141213, … Mediates succinate triggered intracelleular calcium mobilization, induces migratory responses and acts in synergy with Toll-like receptor ligands for the production of proinflammatory cytokines as well

    Polypeptides: Succinate receptor 1Synonyms: G protein-coupled receptor 91
  6. Target

    Neuromedin-K receptor

    go.drugbank.com/bio_entities/BE0002371
    TargetHumans

    Neuromedin-K binding to its receptor triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C (PubMed:37391393). … The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K and substance P (PubMed:1312036).

    Polypeptides: Neuromedin-K receptorSynonyms: NK-3 receptor, Neurokinin B receptor
  7. Target

    B2 bradykinin receptor

    go.drugbank.com/bio_entities/BE0003513
    TargetHumans

    Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system

    Polypeptides: B2 bradykinin receptorSynonyms: BK-2 receptor
  8. Target

    Ryanodine receptor 3

    go.drugbank.com/bio_entities/BE0005296
    TransporterTargetHumans

    Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction (PubMed:12354756, PubMed:9395096). May...

    Polypeptides: Ryanodine receptor 3Synonyms: Type 3 ryanodine receptor, Brain-type ryanodine receptor
  9. Target

    5HT3 serotonin receptor

    go.drugbank.com/bio_entities/BE0005582
    TargetHumans

    Polypeptides: 5HT3 serotonin receptor
  10. Target

    B1 bradykinin receptor

    go.drugbank.com/bio_entities/BE0005831
    TargetHumans

    This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation

    Polypeptides: B1 bradykinin receptorSynonyms: BK-1 receptor