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Displaying results 8941 - 8950 of 10000 in total
  1. Target

    Tubulin beta-3 chain

    go.drugbank.com/bio_entities/BE0001415
    TargetHumans

    Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed:34996871, PubMed:38305685, PubMed:38609661). Microtubules grow by the addition of GTP-tubulin dimers to the mi...

    Polypeptides: Tubulin beta-3 chainSynonyms: Tubulin beta-4 chain
  2. Target

    Chloramphenicol 3-O phosphotransferase

    go.drugbank.com/bio_entities/BE0001493
    TargetEnzymeStreptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

    Inactivates chloramphenicol by catalyzing the transfer of the gamma-phosphate of ATP to the antibiotic's C-3' hydroxyl group.

    Polypeptides: Chloramphenicol 3-O phosphotransferase
  3. Target

    Prolyl 3-hydroxylase 1

    go.drugbank.com/bio_entities/BE0002202
    TargetEnzymeHumans

    Has prolyl 3-hydroxylase activity and catalyzes the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in pro-collagen chains, a critical step for the formation of mature collagen

    Polypeptides: Prolyl 3-hydroxylase 1
  4. Target

    Prolyl 3-hydroxylase OGFOD1

    go.drugbank.com/bio_entities/BE0002210
    TargetHumans

    Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency.

    Polypeptides: Prolyl 3-hydroxylase OGFOD1Synonyms: uS12 prolyl 3-hydroxylase, 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1
  5. Target

    Prostaglandin E synthase 3

    go.drugbank.com/bio_entities/BE0002480
    TargetHumans

    Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-depende...

    Polypeptides: Prostaglandin E synthase 3
  6. Target

    Glyceraldehyde-3-phosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0002606
    TargetGeobacillus stearothermophilus

    Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.

    Polypeptides: Glyceraldehyde-3-phosphate dehydrogenaseSynonyms: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase
  7. Target

    Peptidoglycan recognition protein 3

    go.drugbank.com/bio_entities/BE0003077
    TargetHumans

    Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to...

    Polypeptides: Peptidoglycan recognition protein 3
  8. Target

    Indole-3-pyruvate decarboxylase

    go.drugbank.com/bio_entities/BE0003274
    TargetEnterobacter cloacae

    Polypeptides: Indole-3-pyruvate decarboxylase
  9. Target

    GTP 3',8-cyclase

    go.drugbank.com/bio_entities/BE0003313
    TargetStaphylococcus aureus (strain MW2)

    Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.

    Polypeptides: GTP 3',8-cyclaseFunction: 4 iron, 4 sulfur cluster binding
  10. Target

    Somatostatin receptor type 3

    go.drugbank.com/bio_entities/BE0003529
    TargetHumans

    Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase

    Polypeptides: Somatostatin receptor type 3Synonyms: SS-3-R