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Displaying results 81 - 90 of 5418 in total
  1. Target

    Arsenite methyltransferase

    go.drugbank.com/bio_entities/BE0005015
    TargetEnzymeHumans

    Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals (PubMed:16407288, PubMed:25997655). It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is redu...

    Synonyms: S-adenosyl-L-methionine:arsenic(III) methyltransferase
  2. Target

    Methionine synthase

    go.drugbank.com/bio_entities/BE0003310
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

    Synonyms: 5-methyltetrahydrofolate S-homocysteine methyltransferase
  3. Target

    ATP-citrate synthase

    go.drugbank.com/bio_entities/BE0009867
    TargetEnzymeHumans

    Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate in multiple biochemical reactions in protein, carbohydrate and lipid metabolism

    Synonyms: ATP-citrate (pro-S-)-lyase
  4. Target

    Protein S100-A2

    go.drugbank.com/bio_entities/BE0003602
    TargetHumans

    May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May a...

    Synonyms: Protein S-100L
  5. Target

    Cytochrome P450 2C19

    go.drugbank.com/bio_entities/BE0003536
    EnzymeTargetHumans

    Oxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol (PubMed:11950794). … Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine

    Synonyms: (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase
  6. Target

    Quinoprotein glucose dehydrogenase B

    go.drugbank.com/bio_entities/BE0001728
    TargetEnzymeAcinetobacter calcoaceticus

    Oxidizes glucose to gluconolactone.

    Synonyms: s-GDH
  7. Target

    Creatine Kinases

    go.drugbank.com/bio_entities/BE0009627
    EnzymeTargetHumans

    Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) (PubMed:8186255). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energ...

    Polypeptides: Creatine kinase S-type, mitochondrialSynonyms: S-MtCK
  8. Target

    Lactoylglutathione lyase

    go.drugbank.com/bio_entities/BE0000962
    TargetEnzymeHumans

    Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294).

    Synonyms: S-D-lactoylglutathione methylglyoxal lyase
  9. Target

    ATP-binding cassette sub-family C member 1

    go.drugbank.com/bio_entities/BE0000785
    TargetTransporterHumans

    Exports S-geranylgeranyl-glutathione (GGG) in lymphoid cells and stromal compartments of lymphoid organs. … Mediates basolateral export of GSH-conjugated R- and S-prostaglandin A2 diastereomers in polarized epithelial cells (PubMed:9426231).

    Synonyms: Glutathione-S-conjugate-translocating ATPase ABCC1Function: ABC-type glutathione S-conjugate transporter activity
  10. Target

    Glutamate mutase sigma subunit

    go.drugbank.com/bio_entities/BE0001771
    TargetClostridium tetanomorphum

    Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).

    Synonyms: Glutamate mutase S chain