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IAG-nucleoside hydrolase
go.drugbank.com/bio_entities/BE0003286TargetTrypanosoma vivaxPolypeptides: IAG-nucleoside hydrolaseFunction: hydrolase activity, hydrolyzing N-glycosyl compoundsEpoxide hydrolase B
go.drugbank.com/bio_entities/BE0003964TargetMycobacterium tuberculosisCatalyzes the hydrolysis of small aromatic epoxide-containing substrates such as trans-1,3-diphenylpropene oxide, trans and cis-stilbene oxide, and terpenoid epoxide.
Polypeptides: Epoxide hydrolase BSynonyms: Epoxide hydrolase, SubName: PROBABLE EPOXIDE HYDROLASE EPHB (EPOXIDE HYDRATASE)Lactase/phlorizin hydrolase
go.drugbank.com/bio_entities/BE0004338TargetHumansThe mature protein is composed of two domains that catalyze the hydrolysis of beta-glucopyranosides and beta-galactopyranosides, with a preference for hydrophilic aglycones (in lactose and cellobiose) … Broad specificity glycosidase of the intestinal brush border membrane that hydrolyzes lactose, the main sugar in mammalian milk, to produce D-glucose and D-galactose (PubMed:12594539, PubMed:16400612,
Polypeptides: Lactase/phlorizin hydrolaseSerine hydrolase BPHL
go.drugbank.com/bio_entities/BE0004370TargetHumansSpecific alpha-amino acid ester serine hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary … Catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir, converting them into their active forms (acyclovir and ganciclovir) (PubMed
Polypeptides: Serine hydrolase BPHLSynonyms: Valacyclovir hydrolase, Biphenyl hydrolase-like proteinEpoxide hydrolase 1
go.drugbank.com/bio_entities/BE0009565EnzymeHumansBiotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water (By similarity). … Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol (PubMed:24958911). Binds 20(S)-hydroxycholesterol (20(S)-OHC) (By similarity)
Polypeptides: Epoxide hydrolase 1Synonyms: Microsomal epoxide hydrolaseCarboxylic ester hydrolase
go.drugbank.com/bio_entities/BE0009693EnzymeHumansPolypeptides: Carboxylic ester hydrolaseFunction: carboxylic ester hydrolase activitySerine hydrolase RBBP9
go.drugbank.com/bio_entities/BE0011987TargetHumansSerine hydrolase (Probable) (PubMed:32196348). … May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1
Polypeptides: Serine hydrolase RBBP9Function: serine hydrolase activityProlyl 3-hydroxylase OGFOD1
go.drugbank.com/bio_entities/BE0002210TargetHumansProlyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation
Synonyms: Termination and polyadenylation 1 homolog, 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1Bifunctional epoxide hydrolase 2
go.drugbank.com/bio_entities/BE0000950TargetEnzymeHumansThe C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides (PubMed:12574510, PubMed:12869654, PubMed:22798687).
Polypeptides: Bifunctional epoxide hydrolase 2GDP-mannose mannosyl hydrolase
go.drugbank.com/bio_entities/BE0001756TargetEscherichia coli (strain K12)Hydrolyzes both GDP-mannose and GDP-glucose (PubMed:10913267, PubMed:23481913, PubMed:7592609).
Polypeptides: GDP-mannose mannosyl hydrolase